卵巢癌伴甲状腺转移导致临床甲状腺功能减退：一例报告
Ovarian carcinoma with thyroid metastases causing clinical hypothyroidism: a case report.
作者信息
Skarf Lara M, Dezube Bruce J, Bryan Bradley, Berkenblit Anna
机构信息
Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, CC-913, Boston, MA 02215, USA.
出版信息
Gynecol Oncol. 2006 Aug;102(2):394-6. doi: 10.1016/j.ygyno.2006.02.018. Epub 2006 Mar 29.
BACKGROUND
Ovarian cancer is known to metastasize to the thyroid gland. Despite an incidence of ovarian metastasis to the thyroid of 3-15%, clinical hypothyroidism resulting from such metastasis has not yet been reported. We present a case of metastatic ovarian cancer to the thyroid resulting in clinical hypothyroidism.
CASE
A 55-year-old woman with recurrent papillary adenocarcinoma of the ovary presented with fatigue, abdominal distention, lymphedema, and depression. Thyroid stimulating hormone was markedly elevated, and thyroid biopsy demonstrated bilateral metastatic ovarian carcinoma.
CONCLUSION
Although uncommon, metastatic disease to the thyroid should be considered when evaluating a patient with advanced ovarian cancer and clinical hypothyroidism.
背景
已知卵巢癌会转移至甲状腺。尽管卵巢转移至甲状腺的发生率为3% - 15%，但尚未有因这种转移导致临床甲状腺功能减退的报道。我们报告一例转移性卵巢癌至甲状腺导致临床甲状腺功能减退的病例。
病例
一名55岁复发性卵巢乳头状腺癌女性患者，出现疲劳、腹胀、淋巴水肿和抑郁症状。促甲状腺激素显著升高，甲状腺活检显示双侧转移性卵巢癌。
结论
尽管罕见，但在评估晚期卵巢癌和临床甲状腺功能减退患者时，应考虑甲状腺转移瘤。
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