先天性病毒感染的实验室评估与诊断：风疹、巨细胞病毒（CMV）、水痘带状疱疹病毒（VZV）、单纯疱疹病毒（HSV）、细小病毒B19和人类免疫缺陷病毒（HIV）。

Laboratory assessment and diagnosis of congenital viral infections: Rubella, cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV).

作者信息

Mendelson Ella, Aboudy Yair, Smetana Zahava, Tepperberg Michal, Grossman Zahava

机构信息

Central Virology Laboratory, Ministry of Health and Faculty of Life Sciences, Bar-Ilan University, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

出版信息

Reprod Toxicol. 2006 May;21(4):350-82. doi: 10.1016/j.reprotox.2006.02.001. Epub 2006 Mar 27.

DOI:10.1016/j.reprotox.2006.02.001

PMID:16564672

Abstract

Viral infections during pregnancy may cause fetal or neonatal damage. Clinical intervention, which is required for certain viral infections, relies on laboratory tests performed during pregnancy and at the neonatal stage. This review describes traditional and advanced laboratory approaches and testing methods used for assessment of the six most significant viral infections during pregnancy: rubella virus (RV), cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV). Interpretation of the laboratory tests results according to studies published in recent years is discussed.

摘要

孕期病毒感染可能导致胎儿或新生儿损伤。某些病毒感染所需的临床干预依赖于孕期和新生儿阶段进行的实验室检查。本综述描述了用于评估孕期六种最重要病毒感染的传统和先进实验室方法及检测手段，这六种病毒感染分别为风疹病毒（RV）、巨细胞病毒（CMV）、水痘-带状疱疹病毒（VZV）、单纯疱疹病毒（HSV）、细小病毒B19和人类免疫缺陷病毒（HIV）。文中还讨论了根据近年来发表的研究对实验室检查结果的解读。