Mel'nichenko E M, Mikhaĭlovskaia V P
Stomatologiia (Mosk). 1991 May-Jun;70(3):57-9.
Two groups of children suffering from acute herpetic stomatitis were under study. 214 patients were referred to a group at risk of developing a chronic form of the condition on the basis of mathematical prediction. The immunofluorescent antibody technique was used to detect herpes simplex virus antigen in the peripheral blood leukocytes of healthy children and patients. The studies have shown inadequate humoral and local immunologic defense in the children referred to the risk group; herpes simplex antigen was more often detectable in their blood leukocytes than in the reference group.
对两组患有急性疱疹性口炎的儿童进行了研究。根据数学预测,将214名患者归为有发展为该病慢性形式风险的一组。采用免疫荧光抗体技术检测健康儿童和患者外周血白细胞中的单纯疱疹病毒抗原。研究表明,被归为风险组的儿童体液免疫和局部免疫防御不足;与参照组相比,他们的血白细胞中更常检测到单纯疱疹抗原。