Howard Andrew D
Metropolitan Nephrology Associates, Alexandria, VA 22306, USA.
Am J Kidney Dis. 2006 Apr;47(4 Suppl 2):S111-24. doi: 10.1053/j.ajkd.2005.12.040.
Improvements in transplantation practices, immunosuppressive agents, and management of comorbid conditions have led to better outcomes for kidney transplant recipients. Transplantation has become the treatment of choice for patients with end-stage renal disease (ESRD). This has resulted in continued growth in the number of patients living with a functioning kidney allograft as a percentage of the total ESRD population. These patients require long-term follow-up care, which already is straining the limited resources of transplant centers. Community nephrologists are the logical choice to assume responsibility for the posttransplantation care of these patients after discharge from transplant centers when they are stabilized. Optimal management of kidney transplant recipients depends on regular interactive communication between the patient's community nephrologist and the transplant center. Open communication will not only facilitate the initial transition of care, it also will decrease the frequency of referrals back to the transplant center. In an ideal situation, the transplant center and community nephrologist would develop and discuss plans for discharge and transition of care for the individual patient before the actual kidney transplantation. Important issues for effective communication include changes in laboratory results and kidney function; pretransplantation and posttransplantation comorbid conditions, surgical complications, or adverse effects of medications; modifications to immunosuppressive therapy or other medications; recurrent hospitalizations or emergency care; and changes in biopsy results.
移植技术、免疫抑制剂以及合并症管理方面的改进,已使肾移植受者获得了更好的治疗效果。移植已成为终末期肾病(ESRD)患者的首选治疗方法。这导致拥有功能良好的同种异体肾移植的患者数量在ESRD总人口中所占的比例持续增长。这些患者需要长期的随访护理,这已经使移植中心有限的资源不堪重负。当肾移植患者出院病情稳定后,社区肾病科医生是承担其移植后护理责任的合理人选。肾移植受者的最佳管理取决于患者的社区肾病科医生与移植中心之间定期的互动沟通。开放的沟通不仅有助于护理的初始过渡,还会减少转回移植中心的转诊频率。在理想情况下,移植中心和社区肾病科医生会在实际肾移植之前就为个体患者制定并讨论出院和护理过渡计划。有效沟通的重要问题包括实验室检查结果和肾功能的变化;移植前和移植后的合并症、手术并发症或药物不良反应;免疫抑制治疗或其他药物的调整;再次住院或急诊护理;以及活检结果的变化。