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罕见、特殊及非典型:一例因皮质发育异常所致的额叶癫痫病例

Uncommon, exceptional and atypical: a case of frontal lobe epilepsy due to cortical dysplasia.

作者信息

Grant Arthur C, Kim Richard B

机构信息

Department of Neurology, New York University School of Medicine, USA.

出版信息

Epileptic Disord. 2006 Mar;8(1):73-6.

PMID:16567331
Abstract

We report a case of frontal lobe epilepsy due to focal cortical dysplasia that included three independent unusual features. The patient, a 45-year-old, right-handed woman, had her first seizure at age 29, well into adulthood. Seizures had been easily controlled with medication for 15 years, then without provocation they became medically intractable during a single, identifiable day. Resection of the dysplastic tissue in the posterior dorsolateral right frontal cortex rendered the patient seizure-free, but produced a significant, non-fluent, Broca type, crossed aphasia. In addition, the seizure semiology was striking and remarkable, a common finding in frontal lobe epilepsy. [Published with video sequences].

摘要

我们报告了一例因局灶性皮质发育异常导致的额叶癫痫病例,该病例具有三个独立的不寻常特征。患者为一名45岁右利手女性,29岁时首次发作癫痫,已步入成年期。癫痫发作曾通过药物轻松控制了15年,然后在某一天,毫无诱因地突然变得药物难治。切除右侧额后外侧皮质的发育异常组织后,患者癫痫发作停止,但出现了严重的、非流利型、布罗卡型交叉性失语。此外,癫痫发作的症状学显著且引人注目,这在额叶癫痫中是常见的发现。[随视频序列发表]

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