Gazmararian J A, Foxman B, Yen L T, Morgenstern H, Edington D W
School of Public Health, University of Michigan, Ann Arbor 48109-2214.
Am J Public Health. 1991 Oct;81(10):1296-301. doi: 10.2105/ajph.81.10.1296.
From 1986 to 1987 the Carter Center of Emory University joined with the Centers for Disease Control (CDC) to develop a new, probability-based, adult health risk appraisal (HRA) instrument for the public domain. This new instrument is compared with the CDC HRA version to determine which is a more accurate predictor of mortality.
We compared predicted mortality risks from the CDC HRA and the Carter Center HRA with the observed mortality among 3135 smokers and never-smoking persons, aged 25 to 60, followed from 1959 to 1979 as part of the Tecumseh Community Health Study.
When individuals were classified according to the difference between their actual age and risk age, for the CDC HRA, there was a progressively increasing risk of 10-year mortality as the difference increased. The Carter Center HRA did not show this trend. An analysis using relative operating characteristic curves showed that the mortality risk predictions for both programs were very similar for men and women. However, differences between actual age and risk age for the two programs were not similar for men or women, particularly older men. Therefore, actual age minus risk age for the CDC program was a more accurate predictor of 10-year mortality than was this difference for the Carter Center program.
The results from both types of analyses suggest that the validity of risk ages obtained from the Carter Center version may not be sufficient to justify updating programs for those currently using the CDC instrument.
1986年至1987年,埃默里大学卡特中心与疾病控制中心(CDC)合作,为公共领域开发一种新的、基于概率的成人健康风险评估(HRA)工具。将这种新工具与CDC的HRA版本进行比较,以确定哪一个是更准确的死亡率预测指标。
我们将CDC的HRA和卡特中心的HRA预测的死亡风险与1959年至1979年作为蒂康西社区健康研究一部分所追踪的3135名年龄在25至60岁之间的吸烟者和非吸烟者的观察到的死亡率进行了比较。
当根据实际年龄与风险年龄的差异对个体进行分类时,对于CDC的HRA,随着差异的增加,10年死亡率风险逐渐增加。卡特中心的HRA未显示出这种趋势。使用相对操作特征曲线进行的分析表明,两个项目对男性和女性的死亡风险预测非常相似。然而,两个项目的实际年龄与风险年龄之间的差异在男性或女性中并不相似,尤其是老年男性。因此,CDC项目的实际年龄减去风险年龄比卡特中心项目的这一差异更能准确预测10年死亡率。
两种分析结果均表明,从卡特中心版本获得的风险年龄的有效性可能不足以证明为目前使用CDC工具的人群更新项目是合理的。