1型人类免疫缺陷病毒感染儿童接种水痘活疫苗的安全性和免疫原性
Safety and immunogenicity of live varicella virus vaccine in children with human immunodeficiency virus type 1.
作者信息
Armenian Saro H, Han Jin Young, Dunaway Theresa M, Church Joseph A
机构信息
Division of General Pediatrics, Childrens Hospital Los Angeles, University of Southern California, USA.
出版信息
Pediatr Infect Dis J. 2006 Apr;25(4):368-70. doi: 10.1097/01.inf.0000207492.97867.15.
Live varicella virus vaccine was administered to 10 stable human immunodeficiency virus type 1 (HIV-1)-infected children. Subjects were monitored for adverse reactions, HIV-1 plasma levels, CD4 T cell counts and immune responses. The vaccine was well-tolerated. Varicella-zoster virus-specific lymphocyte proliferative responses were detected in all subjects by 4 weeks and in 9 of 10 subjects 1 year after vaccination.
对10名病情稳定的1型人类免疫缺陷病毒（HIV-1）感染儿童接种了水痘活病毒疫苗。对受试者进行了不良反应、HIV-1血浆水平、CD4 T细胞计数和免疫反应的监测。该疫苗耐受性良好。接种疫苗4周后，所有受试者均检测到水痘-带状疱疹病毒特异性淋巴细胞增殖反应，1年后10名受试者中有9名检测到该反应。
Zotero 插件