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左布比卡因和罗哌卡因用于锁骨下臂丛神经阻滞

Levobupivacaine and ropivacaine in the infraclavicular brachial plexus block.

作者信息

Piangatelli C, De Angelis C, Pecora L, Recanatini F, Cerchiara P, Testasecca D

机构信息

Division of Anesthesia and Resuscitation, Ospedali Riuniti, Ancona, Italy.

出版信息

Minerva Anestesiol. 2006 Apr;72(4):217-21.

Abstract

AIM

Infraclavicular brachial plexus block were first described by Raj, yet this block remained underutilized despite theoretical advantages. The aim of this prospective, randomized study was to compare equipotent doses of levobupivacaine and ropivacaine.

METHODS

For this prospective, randomized study we have enrolled, after informed consent, 30 patients of both sexes, ASA status I-II, who were going to receive surgery to the forearm or hand with tourniquet position on the arm. The infraclavicular plexus block was performed by using vertical technique. The block was performed with 30 mL of levobupivacaine 0.5% or ropivacaine 0.75%.

RESULTS

No differences were reported between 2 groups in terms of demographic data. The onset-time for motor block was greater for ropivacaine group (p<0.05); the sensitive block was longer in levobupivacaine group (p<0.05).

CONCLUSIONS

The long duration of sensory block associated with the with good analgesia, less toxicity and the pharmacodynamic properties of levobupivacaine include this new local anaesthetic as a valid choice respect other local anaesthetic for infraclavicular plexus block.

摘要

目的

锁骨下臂丛神经阻滞最早由拉吉描述,然而尽管有理论上的优势,这种阻滞方法的使用仍然不足。这项前瞻性随机研究的目的是比较等效剂量的左旋布比卡因和罗哌卡因。

方法

在这项前瞻性随机研究中,我们在获得知情同意后,纳入了30例ASA I-II级的男女患者,他们将接受上肢使用止血带的前臂或手部手术。采用垂直技术进行锁骨下臂丛神经阻滞。使用30毫升0.5%的左旋布比卡因或0.75%的罗哌卡因进行阻滞。

结果

两组在人口统计学数据方面没有差异。罗哌卡因组运动阻滞的起效时间更长(p<0.05);左旋布比卡因组感觉阻滞持续时间更长(p<0.05)。

结论

左旋布比卡因具有较长的感觉阻滞时间,同时具有良好的镇痛效果、较低的毒性以及药效学特性,这使得这种新型局部麻醉药成为锁骨下臂丛神经阻滞优于其他局部麻醉药的有效选择。

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