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针对近期发生骨质疏松性骨折患者的疾病管理项目的结果

Outcomes of a disease-management program for patients with recent osteoporotic fracture.

作者信息

Che M, Ettinger B, Liang J, Pressman A R, Johnston J

机构信息

Department of Medicine, Kaiser Permanente Medical Center, 3700 Vaca Valley Parkway, Vacaville, CA 95688-9430, USA.

出版信息

Osteoporos Int. 2006;17(6):847-54. doi: 10.1007/s00198-005-0057-y. Epub 2006 Mar 29.

Abstract

INTRODUCTION

The purpose of this study was to evaluate outcomes of a disease-management program designed to increase rates of bone-mineral-density (BMD) testing and initiation of osteoporosis medication among patients with a recent osteoporotic fracture.

STUDY DESIGN

We identified 744 consecutive patients aged>or=55 years who were seen at either of 2 of 14 Kaiser Permanente medical facilities in Northern California (KPNC) after sustaining a fracture of the hip, spine, wrist, or humerus between April 2003 and May 2004. These patients were invited to participate in a study of the Fragile Fracture Management Program, whose protocol used fracture-risk assessment tools to determine treatment recommendations. Postfracture care of study participants was compared with usual postfracture care received by osteoporotic-fracture patients at 12 other KPNC facilities.

RESULTS

Of the 744 patients who were invited to participate in the study, 293 (39%) agreed to participate, and 169 (23%) completed the evaluation. Of these 169 patients (127 women, 42 men), 65 (51%) of the women and 7 (17%) of the men qualified for drug treatment; of these 72 patients, 6 (86%) of the men and 41 (63%) of the women accepted the offered treatment. At the two study locations, rates of care (BMD testing or prescribing osteoporosis medication) were about twice as high as rates of usual postfracture care observed at 12 other medical centers in KPNC.

CONCLUSIONS

Compared with patients who received usual care for osteoporotic fracture, patients participating in a postfracture disease management program had substantially higher rates of medical attention given for osteoporosis; however, the overall yield of the program was low. This low uptake rate was related to factors not previously appreciated: many patients refused participation in the program; a high proportion of younger women-and men of all ages-did not qualify for treatment; and treatment was refused by one in three study-qualified women and by one in seven study-qualified men. Additional efforts are needed to overcome patient barriers to improved osteoporosis evaluation, treatment and participation in postfracture programs.

摘要

引言

本研究旨在评估一项疾病管理项目的效果,该项目旨在提高近期发生骨质疏松性骨折患者的骨密度(BMD)检测率及启动骨质疏松药物治疗的比例。

研究设计

我们确定了744例年龄≥55岁的连续患者,这些患者于2003年4月至2004年5月期间在北加利福尼亚州凯撒医疗集团(KPNC)的14家医疗机构中的2家,因髋部、脊柱、腕部或肱骨骨折前来就诊。这些患者被邀请参与一项脆性骨折管理项目的研究,该项目方案使用骨折风险评估工具来确定治疗建议。将研究参与者的骨折后护理情况与KPNC其他12家医疗机构中骨质疏松性骨折患者接受的常规骨折后护理情况进行比较。

结果

在被邀请参与研究的744例患者中,293例(39%)同意参与,169例(23%)完成了评估。在这169例患者(127例女性,42例男性)中,65例(51%)女性和7例(17%)男性符合药物治疗条件;在这72例患者中,6例(86%)男性和41例(63%)女性接受了提供的治疗。在两个研究地点,护理率(BMD检测或开具骨质疏松药物)约为KPNC其他12家医疗中心观察到的常规骨折后护理率的两倍。

结论

与接受骨质疏松性骨折常规护理的患者相比,参与骨折后疾病管理项目的患者接受骨质疏松医疗护理的比例显著更高;然而,该项目的总体收益较低。这种低参与率与之前未认识到的因素有关:许多患者拒绝参与该项目;很大一部分年轻女性以及所有年龄段的男性不符合治疗条件;三分之一符合研究条件的女性和七分之一符合研究条件的男性拒绝治疗。需要做出更多努力来克服患者在改善骨质疏松评估、治疗及参与骨折后项目方面的障碍。

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