卵胞浆内单精子注射术后的肢端与肾脏畸形

Acral and renal malformations following ICSI.

作者信息

Schuffner A, Centa L, Reggiani C, Costa S

机构信息

Androlab - Clínica e Laboratório de Reprodução Humana e Andrologia, Curitiba, Brazil.

出版信息

Arch Androl. 2006 May-Jun;52(3):145-8. doi: 10.1080/01485010500379863.

DOI:10.1080/01485010500379863

PMID:16574593

Abstract

This case reports a delivery of a child with limb and renal malformations following intracytoplasmic sperm injection. A 29-year-old woman and a 39-year-old man with primary infertility underwent IVF-ICSI-ET therapy cycle. The couple delivered an infant with acrorenal syndrome. When assisted reproductive techniques are used, especially ICSI, the risk of genetics abnormalities should be discussed in detail with the couple and sufficient informed consent should be obtained before starting IVF-ET procedures.

摘要

本病例报告了1例经卵胞浆内单精子注射后分娩出的伴有肢体和肾脏畸形的患儿。一名29岁的女性和一名39岁的原发性不孕男性接受了体外受精-卵胞浆内单精子注射-胚胎移植治疗周期。这对夫妇分娩出一名患有肢端肾综合征的婴儿。当使用辅助生殖技术，尤其是卵胞浆内单精子注射时，应与夫妇详细讨论遗传异常的风险，并在开始体外受精-胚胎移植程序前获得充分的知情同意。