Giles Matthew F, Flossman Enrico, Rothwell Peter M
Department of Clinical Neurology, Oxford University, London, UK.
Stroke. 2006 May;37(5):1254-60. doi: 10.1161/01.STR.0000217388.57851.62. Epub 2006 Mar 30.
Little research has been done on patients' behavior after transient ischemic attack (TIA). Recent data on the high early risk of stroke after TIA mean that emergency action after TIA is essential for effective secondary prevention. We therefore studied patients' behavior immediately after TIA according to their perceptions, clinical characteristics, and predicted stroke risk.
Consecutive patients with TIA participating in the Oxford Vascular Study or attending dedicated hospital clinics in Oxfordshire, UK, were interviewed. Predicted stroke risk was calculated using 2 validated scores.
Of 241 patients, 107 (44.4%) sought medical attention within hours of the event, although only 24 of these attended the emergency department. A total of 107 (44.4%) delayed seeking medical attention for > or =1 day. Correct recognition of symptoms (42.2% of patients) was not associated with less delay. However, patients with motor symptoms or duration of symptoms > or =1 hour were more likely to seek emergency attention (hazard ratio, 2.1; 95% CI, 1.4 to 3.2; P=0.00005), as were those at higher predicted stroke risk (P=0.001). The other main correlate with delay was the day of the week on which the TIA occurred (P<0.001), with greater delays at the weekend. Delay was unrelated to age, sex, or other vascular risk factors.
Many patients delay seeking medical attention after a TIA irrespective of correct recognition of symptoms, although patients at higher predicted risk of stroke do act more quickly. Public education about both the urgency and nature of TIA is required.
关于短暂性脑缺血发作(TIA)后患者行为的研究较少。近期有关TIA后早期卒中高风险的数据表明,TIA后的紧急行动对于有效的二级预防至关重要。因此,我们根据患者的认知、临床特征和预测的卒中风险,研究了TIA后患者的即刻行为。
对参与牛津血管研究或在英国牛津郡专门医院门诊就诊的连续TIA患者进行访谈。使用2种经过验证的评分计算预测的卒中风险。
在241例患者中,107例(44.4%)在事件发生数小时内寻求医疗救治,尽管其中只有24例前往急诊科就诊。共有107例(44.4%)延迟寻求医疗救治≥1天。对症状的正确识别(42.2%的患者)与较少延迟无关。然而,有运动症状或症状持续时间≥1小时的患者更有可能寻求紧急救治(风险比为2.1;95%CI为1.4至3.2;P = 0.00005),预测卒中风险较高的患者也是如此(P = 0.001)。与延迟相关的另一个主要因素是TIA发生的星期几(P < 0.001),周末延迟时间更长。延迟与年龄、性别或其他血管危险因素无关。
许多患者在TIA后延迟寻求医疗救治,无论是否正确识别症状,尽管预测卒中风险较高的患者行动更快。需要对公众进行有关TIA紧迫性和性质的教育。