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食用肥料喂养的小家鼠骨髓细胞中染色体断裂的随机性

Randomness of chromosome breaks in bone marrow cells of fertilizer-fed mice, Mus musculus.

作者信息

Chaurasia O P

机构信息

Department of Zoology, Bhagalpur University, India.

出版信息

Cytobios. 1991;67(268):7-12.

PMID:1657535
Abstract

Three commonly used fertilizers, urea, single superphosphate and muriate of potash, induced chromosome and chromatid breaks in the metaphase chromosomes of bone marrow cells of fertilizer-fed Swiss albino mice, Mus musculus. The breaks caused by urea and phosphate were non-randomly distributed, since they were more frequent in the longer chromosomes than in the smaller ones, and more common in the distal region than in the juxtacentromeric and median regions. The breaks induced by muriate of potash were randomly distributed in both the length and region of the chromosomes.

摘要

三种常用肥料,即尿素、过磷酸钙和氯化钾,在以肥料喂养的小家鼠(瑞士白化小鼠)骨髓细胞中期染色体中诱发了染色体和染色单体断裂。尿素和磷酸盐引起的断裂并非随机分布,因为它们在较长染色体中比在较短染色体中更频繁,并且在远端区域比在着丝粒附近区域和中间区域更常见。氯化钾诱发的断裂在染色体的长度和区域上均呈随机分布。

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