Cumulative effect of T-2 toxin and vitamin C on chromosomal abnormalities in the bone marrow cells of mice (Mus musculus).

A regular dose of 10 mg/kg body wt/day of vitamin C as a part of the daily diet markedly reduced T-2 toxin-induced abnormalities in the chromosomal cells in mice (Mus musculus). The preventive effect on individual types of change in chromosomes such as breakages, chromatid gaps, ring formations and widespread fragmentation, was increased.