Ben Arush M W, Peretz-Nahum M, Bar Maor J A, Berant M
Pediatric Surgery Dept., Rambam Medical Center, Haifa.
Harefuah. 1991 May 1;120(9):499-502.
We reviewed epidemiological data and outcome of 134 children with abdominal tumors (AT) among a total of 460 children with solid tumors (ST) seen between 1971-1989. There were no significant differences in ethnic distribution or sex ratio between children with AT and ST. The mean age was younger in those with AT than with ST (4.7 vs 7.2 years). The 3 major histologic AT types were Burkitt lymphoma, Wilms' tumor and neuroblastoma, with a relative increase after 1978 in those with abdominal Burkitt lymphoma. A comparison of our therapeutic results in AT treated before and after 1981 shows significant improvement in the actuarial survival at 5 years: 71.1% of those treated after 1981 were then alive with no evidence of disease, vs only 32.8% of those treated before 1981. Since 1981 the actuarial survival at 5 years in our children with Wilms' tumor and abdominal Burkitt lymphoma is about 80%.
我们回顾了1971年至1989年间所见的460例实体瘤（ST）患儿中134例腹部肿瘤（AT）患儿的流行病学数据及预后情况。AT患儿与ST患儿在种族分布或性别比例上无显著差异。AT患儿的平均年龄比ST患儿小（4.7岁对7.2岁）。AT的3种主要组织学类型为伯基特淋巴瘤、肾母细胞瘤和神经母细胞瘤，1978年后腹部伯基特淋巴瘤患儿相对增多。对1981年前后治疗的AT患儿的治疗结果进行比较显示，5年精算生存率有显著提高：1981年后接受治疗的患儿中有71.1%存活且无疾病证据，而1981年前接受治疗的患儿中这一比例仅为32.8%。自1981年以来，我们的肾母细胞瘤和腹部伯基特淋巴瘤患儿的5年精算生存率约为80%。
