Dammann Olaf, Leviton Alan
Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany.
Semin Fetal Neonatal Med. 2006 Oct;11(5):363-8. doi: 10.1016/j.siny.2006.02.003. Epub 2006 Mar 31.
Antenatal intrauterine infection and the fetal inflammatory response appear to be important pathogenetic factors in preterm birth and subsequent neonatal disorders of the lung and brain. In this paper, we expand this concept to include visual dysfunction. Although present data tend to support our notion, we suggest that more experimental and epidemiological research is needed to elucidate mechanisms of infection/inflammation-induced damage to the eye and visual brain pathways of preterm infants.
产前宫内感染和胎儿炎症反应似乎是早产及随后发生的肺部和脑部新生儿疾病的重要致病因素。在本文中，我们拓展了这一概念，将视觉功能障碍也涵盖在内。尽管现有数据倾向于支持我们的观点，但我们认为需要更多的实验和流行病学研究来阐明感染/炎症对早产儿眼睛和视觉脑通路造成损害的机制。
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