Shors Stephanie M, Cotts William G, Pavlovic-Surjancev Biljana, Gheorghiade Mihai, Carr James C, McCarthy Richard M, Pereles Scott F, Finn Paul J
Department of Radiology, Division of Cardiology, Feinberg School of Medicine, Northwestern University, 251 East Huron Street, Chicago, IL, 60611-3864, USA.
Heart Fail Rev. 2005 Dec;10(4):265-73. doi: 10.1007/s10741-005-7540-6.
To assess the feasibility of a fast, flow-insensitive magnetic resonance imaging (MRI) protocol in heart failure patients for the evaluation of cardiac function, cardiovascular anatomy, and myocardial viability.
Thirty-two consecutive patients with left ventricular (LV) systolic dysfunction and 13 control subjects were prospectively evaluated with MRI. The exam consisted of cine imaging with a steady-state free precession sequence, followed by time-resolved, three-dimensional angiography and delayed, contrast-enhanced imaging. Multiple LV parameters were evaluated, and the heart failure and control results were compared. In 12 patients, MRI-determined ejection fractions were compared to echocardiographic values. Additionally, a qualitative analysis of the cine images was performed. The cardiac MR evaluation yielded diagnostic-quality images in all subjects. Mean imaging time was 37 min. MRI demonstrated significant differences between the heart failure and control subjects in all parameters assessed (p < 0.05). MRI-determined ejection fractions correlated strongly with echocardiographic values (R = 0.75), although the limits of agreement were wide (-17.3%-18.3%).
Using fast, flow-insensitive imaging techniques, MRI is feasible in heart failure for the derivation of more independent indices of cardiac status than any other non-invasive test. Although further investigation is warranted, MRI may prove uniquely helpful in heart failure diagnosis and management.
评估一种快速、血流不敏感的磁共振成像（MRI）方案在心力衰竭患者中用于评估心脏功能、心血管解剖结构和心肌活力的可行性。
对32例连续的左心室（LV）收缩功能障碍患者和13例对照受试者进行了MRI前瞻性评估。检查包括使用稳态自由进动序列的电影成像，随后是时间分辨三维血管造影和延迟对比增强成像。评估了多个左心室参数，并比较了心力衰竭患者和对照者的结果。在12例患者中，将MRI测定的射血分数与超声心动图值进行了比较。此外，对电影图像进行了定性分析。心脏磁共振评估在所有受试者中均产生了诊断质量的图像。平均成像时间为37分钟。MRI显示心力衰竭患者和对照者在所有评估参数上存在显著差异（p < 0.05）。MRI测定的射血分数与超声心动图值高度相关（R = 0.75），尽管一致性界限较宽（-17.3%-18.3%）。
使用快速、血流不敏感的成像技术，MRI在心力衰竭患者中是可行的，可得出比任何其他非侵入性检查更独立的心脏状态指标。尽管有必要进一步研究，但MRI可能在心力衰竭的诊断和管理中证明具有独特的帮助。
