Wong Peerapon, Intragumtornchai Tanin
Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok.
J Med Assoc Thai. 2006 Jan;89(1):63-7.
The incidence and etiologies of hospital-acquired anemia has not been well defined A prospective study was conducted to determine the incidence and etiologies of hospital-acquired anemia developed in patients admitted in the medical ward of a tertiary care university hospital.
All non-anemic (hemoglobin (Hb) > or = 13 g/dl in male, > or = 12 g/dl in female) patients who were admitted to the general medical wards for at least 1 week, between March 2001 to October 2001, were included in the present study. Outcome of interest was anemia developed during hospital stay. The total volume of blood collected for investigations were recorded.
Of the 98 evaluable patients, 64 (65.3%) developed anemia. Thirty-five percent of the patients had mild anemia (Hb > 10.0 g/dl) and 7% had severe anemia (Hb < or = 8.0 g/dl). Anemia of chronic disease was the most common cause found in 57.4% of anemic patients. Mean total volume of blood collected for investigation was higher in the anemic compared with the non-anemic group (147.0 ml vs. 52.0 ml, p < 0.05). Total volume of investigational blood also correlated significantly with degree of anemia (r = 0.638, p < 0.05).
Anemia was a common complication occurring in almost two-thirds of patients admitted to the hospital. Even though anemia of chronic disease was the leading cause, investigational blood loss was also an important contributing factor.
医院获得性贫血的发病率及病因尚未明确。开展了一项前瞻性研究,以确定在一所三级医疗大学医院内科病房住院患者中发生的医院获得性贫血的发病率及病因。
纳入2001年3月至2001年10月期间入住普通内科病房至少1周的所有非贫血患者(男性血红蛋白(Hb)≥13g/dl,女性Hb≥12g/dl)。感兴趣的结局是住院期间发生的贫血。记录用于检查而采集的血液总量。
在98例可评估患者中,64例(65.3%)发生贫血。35%的患者为轻度贫血(Hb>10.0g/dl),7%的患者为重度贫血(Hb≤8.0g/dl)。慢性病贫血是最常见的病因,见于57.4%的贫血患者。与非贫血组相比,贫血组用于检查而采集的血液平均总量更高(147.0ml对52.0ml,p<0.05)。检查用血总量也与贫血程度显著相关(r=0.638,p<0.05)。
贫血是几乎三分之二住院患者中常见的并发症。尽管慢性病贫血是主要原因,但检查失血也是一个重要的促成因素。