Mandavilli U, Schmidt J, Rattner D W, Watson W T, Warshaw A L
Department of Surgery, Massachusetts General Hospital, Boston.
Lab Anim Sci. 1991 Jun;41(3):258-61.
We describe a novel technique for complete and continuous bladder urine collection in conscious unrestrained rats. After urethral ligation, a silastic catheter is placed through a flexible steel tether, tunneled subcutaneously from the posterior neck area to a suprapubic incision, and inserted and fixed into the exposed urinary bladder. The catheter drains by gravity into a dependent collecting vessel protected from contamination by feces or food.
