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迷失在语义空间:语义性痴呆中特征知识的多模态、非言语评估

Lost in semantic space: a multi-modal, non-verbal assessment of feature knowledge in semantic dementia.

作者信息

Garrard Peter, Carroll Erin

机构信息

University College London, Institute of Cognitive Neuroscience, Alexandra House, Hampstead, London, UK.

出版信息

Brain. 2006 May;129(Pt 5):1152-63. doi: 10.1093/brain/awl069. Epub 2006 Apr 3.

Abstract

A novel, non-verbal test of semantic feature knowledge is introduced, enabling subordinate knowledge of four important concept attributes--colour, sound, environmental context and motion--to be individually probed. This methodology provides more specific information than existing non-verbal semantic tests about the status of attribute knowledge relating to individual concept representations. Performance on this test of a group of 12 patients with semantic dementia (10 male, mean age: 64.4 years) correlated strongly with their scores on more conventional tests of semantic memory, such as naming and word-to-picture matching. The test's overlapping structure, in which individual concepts were probed in two, three or all four modalities, provided evidence of performance consistency on individual items between feature conditions. Group and individual analyses revealed little evidence for differential performance across the four feature conditions, though sound and colour correlated most strongly, and motion least strongly, with other semantic tasks, and patients were less accurate on the motion features of living than non-living concepts (with no such conceptual domain differences in the other conditions). The results are discussed in the context of their implications for the place of semantic dementia within the classification of progressive aphasic syndromes, and for contemporary models of semantic representation and organization.

摘要

本文介绍了一种全新的语义特征知识非言语测试方法,该方法能够分别探究四个重要概念属性(颜色、声音、环境背景和运动)的从属知识。与现有的非言语语义测试相比,这种方法能够提供关于与个体概念表征相关的属性知识状态的更具体信息。一组12名语义性痴呆患者(10名男性,平均年龄:64.4岁)在该测试中的表现与他们在更传统的语义记忆测试(如命名和词图匹配)中的得分密切相关。该测试采用重叠结构,即通过两种、三种或所有四种模态对个体概念进行探究,这为特征条件之间个体项目的表现一致性提供了证据。尽管声音和颜色与其他语义任务的相关性最强,而运动与其他语义任务的相关性最弱,并且患者在有生命概念的运动特征方面的准确性低于无生命概念(在其他条件下不存在这种概念领域差异),但群体和个体分析显示,在四个特征条件下几乎没有表现差异的证据。本文将结合这些结果对语义性痴呆在进行性失语综合征分类中的地位以及当代语义表征和组织模型的意义进行讨论。

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