Eade O E, Acheson E D, Cuthbert M F, Hawkes C H
Br Med J. 1975 Apr 12;2(5962):66-7. doi: 10.1136/bmj.2.5962.66.
A patient with seronegative inflammatory polyarthritis developed a predominantly motorperipheral neuropathy associated with the use of indomethacin. Three other cases of peripheral neuropathy associated with indomethacin treatment have been reported to the Committee on Safety of Medicines. In all cases the neuropathy regressed when indomethacinwas stopped. Peripheral neuropathy should be recognized as a rare complication of indomethacin therapy and considered in the differential diagnosis of a neuropathy accompanyingrheumatoid arthritis.
一名血清阴性炎性多关节炎患者在使用吲哚美辛后出现了以运动为主的周围神经病变。另外三例与吲哚美辛治疗相关的周围神经病变已报告给药品安全委员会。在所有病例中，停用吲哚美辛后神经病变均有所缓解。周围神经病变应被视为吲哚美辛治疗的一种罕见并发症，并在类风湿关节炎伴发神经病变的鉴别诊断中予以考虑。
