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[鼻内镜下鼻窦内翻性乳头状瘤的显微切除术]

[Endonasal micro-endoscopic resection of sinonasal inverted papilloma].

作者信息

Minovi A, Kollert M, Draf W, Bockmühl U

机构信息

Klinik für Hals-Nasen-Ohrenkrankheiten, Kopf-, Hals- und Plastische Gesichtschirurgie, Kommunikationsstörungen, Klinikum Fulda gAG, Akademisches Lehrkrankenhaus der Philipps-Universität Marburg.

出版信息

Laryngorhinootologie. 2006 Jun;85(6):421-5. doi: 10.1055/s-2006-925059. Epub 2006 Feb 13.

Abstract

BACKGROUND

The goal of this study was to assess the potentials and limitations of endonasal micro-endoscopic surgery in the treatment of sinonasal inverted papilloma (IP) and to demonstrate long-term results.

PATIENTS AND METHODS

From 1989 to 2005, 64 patients underwent resection of IP via an endonasal approach using either the endoscope or microscope. Charts were reviewed retrospectively for presenting symptoms, radiological and intraoperative data. All patients were followed by endoscopic and MRI control during a period of up to 174 months, median follow-up was 78 months.

RESULTS

Our study group consisted of 26 male and 38 female patients with an average age of 54.3 years. The majority of the patients (67 %) complained of unilateral nasal obstruction. 52 patients (81 %) were referred for primary surgery. In 12 cases (19 %) recurrent tumors were operated. According to the Krouse classification for IP the tumors were staged as T1 = 11 (17 %) cases, T2 = 37 (58 %) and T3 = 14 (22 %). In two patients a squamous cell carcinoma was associated with an IP ( = T4 stage). Most tumors were localized within the nasal cavity (72 %) or the anterior ethmoid (62 %). In 10 patients an infiltration of the bony skull base was present. During the follow-up period 6 patients developed recurrencies corresponding to an overall recurrence rate of 9.4 %.

CONCLUSIONS

The advances in endonasal micro-endoscopic surgery allow both safe and effective removal of IP with low morbidity, and therefore it should be the approach of the first choice. The osteoplastic approach combined with endonasal surgery is suitable in far lateral located IP. Close follow-up is mandatory to ensure the surgical success.

摘要

背景

本研究的目的是评估鼻内镜下微创手术治疗鼻窦内翻性乳头状瘤(IP)的潜力和局限性,并展示长期疗效。

患者与方法

1989年至2005年期间,64例患者通过鼻内镜或显微镜经鼻入路切除IP。回顾病历以获取临床表现、影像学和术中数据。所有患者在长达174个月的时间内接受内镜和MRI检查,中位随访时间为78个月。

结果

我们的研究组包括26例男性和38例女性患者,平均年龄为54.3岁。大多数患者(67%)主诉单侧鼻塞。52例患者(81%)接受初次手术。12例患者(19%)接受复发性肿瘤手术。根据IP的Krouse分类,肿瘤分期为T1 = 11例(17%),T2 = 37例(58%),T3 = 14例(22%)。2例患者的IP合并鳞状细胞癌(= T4期)。大多数肿瘤位于鼻腔(72%)或筛窦前部(62%)。10例患者存在颅骨基底浸润。随访期间6例患者复发,总复发率为9.4%。

结论

鼻内镜下微创手术的进展使IP的安全有效切除成为可能,且发病率低,因此应作为首选方法。骨成形术联合鼻内手术适用于位于外侧的IP。必须密切随访以确保手术成功。

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