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内翻性乳头状瘤:鼻内手术的可行性及87例患者的长期结果

Inverted papilloma: feasibility of endonasal surgery and long-term results of 87 cases.

作者信息

Minovi Amir, Kollert Malte, Draf Wolfgang, Bockmühl Ulrike

机构信息

Department of Otorhinolaryngology, Head and Neck and Facial Plastic Surgery, Klinikum Fulda gAG, Teaching Hospital of the Philipps-University Marburg, Fulda, Germany.

出版信息

Rhinology. 2006 Sep;44(3):205-10.

Abstract

BACKGROUND

The aim of this retrospective study was to assess the potentials and limitations of endonasal micro-endoscopic sinus surgery in the management of sinonasal inverted papilloma (IP) and to demonstrate long-term results.

METHODS

Eighty-seven patients underwent resection of an IP either via an endonasal, an osteoplastic maxillary or frontal sinus or a combined approach. Charts were reviewed for presenting symptoms, tumour stage according to the Krouse classification, surgical management and follow-up status.

RESULTS

Most tumours were staged as T2 or T3 (42.5% each). Sixty-eight (78.2%) patients were referred for primary surgery. Nineteen (21.8%) patients presented with recurrent disease. The majority of IP (70%) were removed via an endonasal micro-endoscopic procedure. In 20 (23%) patients a combined approach was performed. The overall recurrence rate was 10.3%. Referring to endonasal surgery the incidence of recurrent IP was 10% in contrast to 15% after a combined procedure.

CONCLUSION

Our data show that endonasal micro-endoscopic surgery offers an effective and safe treatment modality of IP with insignificant morbidity. Strict application of selection criteria, wide removal of the tumour origin along the subperiosteal plane as well as drilling the underlying bone and close follow-up of patients are mandatory for success.

摘要

背景

本回顾性研究旨在评估鼻内镜下鼻窦微创手术治疗鼻腔鼻窦内翻性乳头状瘤(IP)的潜力和局限性,并展示长期疗效。

方法

87例患者通过鼻内、骨成形性上颌窦或额窦手术或联合手术切除IP。回顾病历以了解患者的症状表现、根据Krouse分类法的肿瘤分期、手术治疗及随访情况。

结果

大多数肿瘤分期为T2或T3(各占42.5%)。68例(78.2%)患者接受初次手术。19例(21.8%)患者为复发性疾病。大多数IP(70%)通过鼻内镜下微创手术切除。20例(23%)患者采用联合手术。总体复发率为10.3%。鼻内手术的IP复发率为10%,联合手术为15%。

结论

我们的数据表明,鼻内镜下微创手术为IP提供了一种有效且安全的治疗方式,并发症发生率低。严格应用选择标准、沿骨膜下平面广泛切除肿瘤起源部位、磨除下方骨质以及对患者进行密切随访是手术成功的关键。

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