[Collagenase of human leukocytes. Its characteristics, function and regulatory mechanisms].

The characteristics of the human neutrophil collagenase and intracellular and extracellular mechanism regulating this enzyme were given. There were presented molecular basis collagenase latent state , activation of latent enzyme form through the system dependent on free oxygen radicals and the role of glutathione peroxidase in the regulation of the activity of the human leukocyte collagenase.