默奇森陨石中的非蛋白质氨基酸。
Nonprotein amino acids in the murchison meteorite.
作者信息
Kvenvolden K A, Lawless J G, Ponnamperuma C
机构信息
Exobiology Division, Ames Research Center, NASA, Moffett Field, California 94305.
出版信息
Proc Natl Acad Sci U S A. 1971 Feb;68(2):486-90. doi: 10.1073/pnas.68.2.486.
Abstract
Twelve nonprotein amino acids appear to be present in the Murchison meteorite. The identity of eight of them has been conclusively established as N-methylglycine, beta-alanine, 2-methylalanine, alpha-amino-n-butyric acid, beta-amino-n-butyric acid, gamma-amino-n-butyric acid, isovaline, and pipecolic acid. Tentative evidence is presented for the presence of N-methylalanine, N-ethylglycine, beta-aminoisobutyric acid, and norvaline. These amino acids appear to be extraterrestrial in origin and may provide new evidence for the hypothesis of chemical evolution.
摘要
默奇森陨石中似乎存在12种非蛋白质氨基酸。其中8种已被明确鉴定为N-甲基甘氨酸、β-丙氨酸、2-甲基丙氨酸、α-氨基正丁酸、β-氨基正丁酸、γ-氨基正丁酸、异缬氨酸和哌啶酸。有初步证据表明存在N-甲基丙氨酸、N-乙基甘氨酸、β-氨基异丁酸和正缬氨酸。这些氨基酸似乎起源于地球之外，可能为化学进化假说提供新的证据。
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本文引用的文献
1
Racemization of amino acids in sediments from saanich inlet, british columbia.卑诗省萨尼奇湾沉积物中氨基酸的外消旋作用。
Science. 1970 Sep 11;169(3950):1079-82. doi: 10.1126/science.169.3950.1079.
2
Alga-like forms in onverwacht series, South Africa: oldest recognized lifelike forms on Earth.南非“非预期岩系”中的藻类形态：地球上最早被识别的类似生命的形态。
Science. 1968 Sep 6;161(3845):1005-8. doi: 10.1126/science.161.3845.1005.
3
Microorganisms three billion years old from the precambrian of South Africa.来自南非前寒武纪的 30 亿岁微生物。
Science. 1966 May 6;152(3723):758-63. doi: 10.1126/science.152.3723.758.
4
Organic Compounds in Carbonaceous Chondrites.
Science. 1965 Sep 24;149(3691):1455-9. doi: 10.1126/science.149.3691.1455.
5
The origin of optical activity.旋光性的起源。
Ann N Y Acad Sci. 1957 Aug 30;69(2):352-68. doi: 10.1111/j.1749-6632.1957.tb49671.x.
6
D-amino acids in animals.动物体内的D-氨基酸。
Science. 1969 Apr 11;164(3876):142-9. doi: 10.1126/science.164.3876.142.
7
Evidence for extraterrestrial amino-acids and hydrocarbons in the Murchison meteorite.默奇森陨石中存在外星氨基酸和碳氢化合物的证据。
Nature. 1970 Dec 5;228(5275):923-6. doi: 10.1038/228923a0.
8
Marine sediments: dating by the racemization of amino acids.海洋沉积物：通过氨基酸消旋作用进行年代测定
Science. 1970 Nov 13;170(3959):730-2. doi: 10.1126/science.170.3959.730.
9
Bio-organic compounds and glassy microparticles in lunar fines and other materials.月球细粒及其他物质中的生物有机化合物和玻璃质微粒。
Science. 1970 Jan 30;167(3918):767-70. doi: 10.1126/science.167.3918.767.
10
Current status of chemical studies on the origin of life.生命起源的化学研究现状。
Space Life Sci. 1968 Mar;1(1):64-96. doi: 10.1007/BF00924231.
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