疏水性氨基酸和蛋白质氨基酸的益生元合成。
Prebiotic synthesis of hydrophobic and protein amino acids.
作者信息
Ring D, Wolman Y, Friedmann N, Miller S L
出版信息
Proc Natl Acad Sci U S A. 1972 Mar;69(3):765-8. doi: 10.1073/pnas.69.3.765.
Abstract
The formation of amino acids by the action of electric discharges on a mixture of methane, nitrogen, and water with traces of ammonia was studied in detail. The presence of glycine, alanine, alpha-amino-n-butyric acid, alpha-aminoisobutyric acid, valine, norvaline, isovaline, leucine, isoleucine, alloisoleucine, norleucine, proline, aspartic acid, glutamic acid, serine, threonine, allothreonine, alpha-hydroxy-gamma-aminobutyric acid, and alpha,gamma-diaminobutyric acid was confirmed by ion-exchange chromatography and gas chromatography-mass spectrometry. All of the primary alpha-amino acids found in the Murchison Meteorite have been synthesized by this electric discharge experiment.
摘要
详细研究了通过对甲烷、氮气、水与痕量氨的混合物施加放电作用来形成氨基酸的过程。通过离子交换色谱法和气相色谱 - 质谱法确认了甘氨酸、丙氨酸、α - 氨基正丁酸、α - 氨基异丁酸、缬氨酸、正缬氨酸、异缬氨酸、亮氨酸、异亮氨酸、别异亮氨酸、正亮氨酸、脯氨酸、天冬氨酸、谷氨酸、丝氨酸、苏氨酸、别苏氨酸、α - 羟基 - γ - 氨基丁酸以及α,γ - 二氨基丁酸的存在。在默奇森陨石中发现的所有主要α - 氨基酸都已通过该放电实验合成出来。
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