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Proc Natl Acad Sci U S A. 1981 Feb;78(2):681-5. doi: 10.1073/pnas.78.2.681.
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引用本文的文献

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Conformation of cyclo(-L-Pro-Gly-)(3) and its Ca and Mg complexes.环(-L-脯氨酰甘氨酰-)(3)及其钙镁配合物的构象。
Proc Natl Acad Sci U S A. 1982 Jul;79(14):4519-22. doi: 10.1073/pnas.79.14.4519.

本文引用的文献

1
Conformation of uncomplexed natural antamanide crystallized from CH(3)CN/H(2)O.从CH(3)CN/H(2)O中结晶出的未络合天然抗痫肽的构象。
Proc Natl Acad Sci U S A. 1979 Apr;76(4):1532-6. doi: 10.1073/pnas.76.4.1532.
2
Conformations of the li-antamanide complex and na-[phe, val]antamanide complex in the crystalline state.晶体状态下锂-安他酰胺配合物和钠-[苯丙氨酸,缬氨酸]安他酰胺配合物的构象。
Proc Natl Acad Sci U S A. 1973 Jun;70(6):1836-40. doi: 10.1073/pnas.70.6.1836.
3
The molecular structure and some transport properties of valinomycin.缬氨霉素的分子结构及一些转运特性。
Biochem Biophys Res Commun. 1969 May 22;35(4):512-8. doi: 10.1016/0006-291x(69)90376-3.
4
The crystal structure of a K+ complex of valinomycin.
Helv Chim Acta. 1975 Mar 12;58(2):432-42. doi: 10.1002/hlca.19750580212.
5
Beauvericin and divalent cations: crystal structure of the barium complex.
Biochem Biophys Res Commun. 1975 May 5;64(1):151-6. doi: 10.1016/0006-291x(75)90231-4.
6
Crystal and molecular structure of complex between cyclo(L-prolylglycyl)4 and RbSCN.环（L-脯氨酰甘氨酰）4与硫氰酸铷复合物的晶体结构和分子结构
J Am Chem Soc. 1977 Jul 6;99(14):4799-4803. doi: 10.1021/ja00456a043.
7
Structural analysis of spermine and magnesium ion binding to yeast phenylalanine transfer RNA.精胺和镁离子与酵母苯丙氨酸转移核糖核酸结合的结构分析。
Proc Natl Acad Sci U S A. 1978 Jan;75(1):64-8. doi: 10.1073/pnas.75.1.64.

从 CH(3)CN 溶液中结晶的环(Gly-L-Pro-L-Pro-Gly-L-Pro-L-Pro)(2)Mg 配合物的构象。

Conformation of cyclo(Gly-L-Pro-L-Pro-Gly-L-Pro-L-Pro)(2)Mg complex crystallized from CH(3)CN solution.

机构信息

Laboratory for the Structure of Matter, Naval Research Laboratory, Washington, D. C. 20375.

出版信息

Proc Natl Acad Sci U S A. 1981 Feb;78(2):681-5. doi: 10.1073/pnas.78.2.681.

DOI:10.1073/pnas.78.2.681
PMID:16592971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC319863/
Abstract

The cyclic hexapeptides (Gly-L-Pro-L-Pro-Gly-L-Pro-L-Pro) in the (peptide-Mg-peptide)(2+) complex have nearly identical asymmetric conformations. Each has two cis Pro-Pro linkages and lacks any intraring hydrogen bonds. The Mg(2+) ion forms six ligands in a regular octahedral array with the carbonyl oxygen atoms of the two Gly residues and one Pro residue of each peptide. The "sandwich" complex has an approximate 2-fold rotation axis through the Mg(2+) relating the two peptide moieties. Cyclo(Gly-Pro-Pro-Gly-Pro-Pro)(2)Mg(ClO(4))(2). 4C(2)H(3)CN crystallizes in space group P3(1) with a = b = 15.744(4) A, c = 24.002(6) A, gamma = 120 degrees , and Z = 3. A highlight of the structure determination is the ready location of the Mg self-vector in a Harker section and the development of the entire structure by use of the tangent formula starting with the known position of the Mg atom.

摘要

在 (peptide-Mg-peptide)(2+) 配合物中的环状六肽 (Gly-L-Pro-L-Pro-Gly-L-Pro-L-Pro) 具有几乎相同的不对称构象。每个都有两个顺式 Pro-Pro 键，并且没有任何环内氢键。Mg(2+) 离子与每个肽的两个 Gly 残基和一个 Pro 残基的羰基氧原子形成一个规则的八面体配位，形成六个配体。“三明治”配合物通过 Mg(2+) 形成一个近似 2 重旋转轴，将两个肽部分联系起来。环 (Gly-Pro-Pro-Gly-Pro-Pro)(2)Mg(ClO(4))(2). 4C(2)H(3)CN 在空间群 P3(1)中结晶，a = b = 15.744(4)A，c = 24.002(6)A，γ = 120 度，Z = 3。结构测定的一个亮点是在 Harker 截面中很容易定位 Mg 自身向量，并且从已知的 Mg 原子位置开始，使用切线公式发展整个结构。