Grudziński I, Szymański A, Chomiczewski K
Department of Food Studies and Nutrition Physiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
Arch Environ Contam Toxicol. 1991 Sep;21(3):462-7. doi: 10.1007/BF01060371.
The intestinal absorption of D-xylose was studied during the subchronic poisoning of male Wistar rats with orally administered potassium nitrate and sodium nitrite associated with exercise; running on a moving track during the last two weeks of poisoning. The metabolic parameters of Na+/K(+)-ATPase, alkaline phosphatase, oxygen uptake, and lactic acid level in the small intestine mucosa were determined one hour after D-xylose treatment. Exercise increased the toxicity of potassium nitrate and sodium nitrite. The experiment demonstrated post-exercise reduction of D-xylose absorption and decrease activity of Na+/K(+)-ATPase and alkaline phosphatase. Exercise caused transient hypoxia of the small intestine, which was observed only in the groups subjected to exercise on the day of the determinations.
在雄性Wistar大鼠经口给予硝酸钾和亚硝酸钠并结合运动进行亚慢性中毒期间，研究了D-木糖的肠道吸收情况；在中毒的最后两周，大鼠在移动跑道上跑步。在给予D-木糖治疗1小时后，测定小肠黏膜中Na+/K(+)-ATP酶、碱性磷酸酶、氧摄取和乳酸水平的代谢参数。运动增加了硝酸钾和亚硝酸钠的毒性。实验表明，运动后D-木糖吸收减少，Na+/K(+)-ATP酶和碱性磷酸酶活性降低。运动导致小肠短暂缺氧，这仅在测定当天进行运动的组中观察到。
