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中风后的手臂功能:经颅磁刺激评估的神经生理相关性及恢复机制

Arm function after stroke: neurophysiological correlates and recovery mechanisms assessed by transcranial magnetic stimulation.

作者信息

Talelli P, Greenwood R J, Rothwell J C

机构信息

Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, 8-11 Queen Square, London WC1N 3BG, UK.

出版信息

Clin Neurophysiol. 2006 Aug;117(8):1641-59. doi: 10.1016/j.clinph.2006.01.016. Epub 2006 Apr 3.

DOI:10.1016/j.clinph.2006.01.016
PMID:16595189
Abstract

Transcranial Magnetic Stimulation has been used for over 20 years to investigate recovery of motor function in stroke patients. In particular, it has been used to quantify the extent of damage to the corticospinal output, reorganisation of the cortical representation of the affected body parts and excitability of intracortical and cortico-cortical circuitries in both hemispheres. In this review, we provide a detailed account of most of the published data with particular reference to methodological issues that affect their interpretation.

摘要

经颅磁刺激已被用于研究中风患者运动功能恢复超过20年。特别是,它已被用于量化皮质脊髓输出的损伤程度、受影响身体部位的皮质代表区的重组以及双侧半球皮质内和皮质-皮质回路的兴奋性。在本综述中,我们详细介绍了大多数已发表的数据,并特别提及影响其解释的方法学问题。

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