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Increased ammonium in culture medium reduces the development of human embryos to the blastocyst stage.

作者信息

Virant-Klun Irma, Tomazevic Tomaz, Vrtacnik-Bokal Eda, Vogler Andrej, Krsnik Mladen, Meden-Vrtovec Helena

机构信息

Department of Obstetrics and Gynecology, Ljubljana, Slovenia.

出版信息

Fertil Steril. 2006 Feb;85(2):526-8. doi: 10.1016/j.fertnstert.2005.10.018.

DOI:10.1016/j.fertnstert.2005.10.018
PMID:16595249
Abstract

The objective of this prospective study was to evaluate the effect of ammonium accumulated in sequential media and determined by enzymatic spectrophotometric method on the blastocyst development in 281 human embryos from 100 stimulated and natural in vitro fertilization (IVF) cycles. Ammonium concentration was increased in 62% of cycles and was correlated negatively with the blastocyst development after classical IVF, but not after intracytoplasmic sperm injection (ICSI).

摘要

相似文献

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