Duffy Lynn, Glass John, Hall Geraldine, Avery Robin, Rackley Raymond, Peterson Scott, Waites Ken
Department of Pathology, WP 230, 619 19th St. South, University of Alabama at Birmingham, Birmingham, AL 35226, USA.
J Clin Microbiol. 2006 Apr;44(4):1590-1. doi: 10.1128/JCM.44.4.1590-1591.2006.
We report the first case of naturally occurring fluoroquinolone resistance in Ureaplasma spp. from the United States. Resistance in this case probably developed as a result of mutations in the gyrA and parC genes of the DNA gyrase/topoisomerase IV complex that occurred in the presence of antimicrobial selective pressure.
我们报告了美国首例自然发生的解脲脲原体对氟喹诺酮耐药的病例。该病例中的耐药性可能是由于在抗菌选择压力存在的情况下,DNA旋转酶/拓扑异构酶IV复合物的gyrA和parC基因发生突变所致。