Collins John
Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.
Fertil Steril. 2006 May;85(5):1364-7; discussion 1368-70. doi: 10.1016/j.fertnstert.2005.10.064. Epub 2006 Apr 5.
Most randomized controlled trials are small relative to the clinical question they address, and chance causes more variability in the results of small trials. Thus, when small studies herald new treatment interventions, clinicians might wish to wait until the body of evidence is weighty and consistent enough to be convincing.
大多数随机对照试验相对于它们所解决的临床问题来说规模较小，而偶然性会在小型试验的结果中导致更多变异性。因此，当小型研究预示着新的治疗干预措施时，临床医生可能希望等到证据足够充分且一致，足以令人信服时再做决定。
