Suzuki Wendy A
Center for Neural Science, New York University, New York, New York 10003, USA.
Neuron. 2006 Apr 6;50(1):19-21. doi: 10.1016/j.neuron.2006.03.029.
How do we encode, store, and retrieve new episodic memories, and what are the computations performed by the hippocampus during this process? One system that has been used to model the brain basis of episodic memory in humans is the study of spatial navigation by path integration in rodents. Here I discuss three exciting new findings focused on encoding or replay of spatial sequences in the rat hippocampus. These findings not only provide important new insight into the computations associated with encoding and consolidation of spatial trajectories, but may also have implications for understanding key aspects of human episodic memory.
我们如何编码、存储和检索新的情景记忆，以及在此过程中海马体执行的计算是什么？一个被用于模拟人类情景记忆的脑基础的系统是对啮齿动物通过路径整合进行空间导航的研究。在此，我将讨论三项令人兴奋的新发现，这些发现聚焦于大鼠海马体中空间序列的编码或重放。这些发现不仅为与空间轨迹编码和巩固相关的计算提供了重要的新见解，而且可能对理解人类情景记忆的关键方面也有启示。
