Henneberger P K, Derk S J, Sama S R, Boylstein R J, Hoffman C D, Preusse P A, Rosiello R A, Milton D K
Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health/CDC, Morgantown, WV 26501, USA.
Occup Environ Med. 2006 Aug;63(8):551-7. doi: 10.1136/oem.2005.024786. Epub 2006 Apr 6.
Workplace conditions can potentially contribute to the worsening of asthma, yet it is unclear what percentage of adults with asthma experience workplace exacerbation of symptoms. The objective of this investigation was to determine the prevalence of workplace exacerbation of asthma (WEA).
Adults with asthma aged 18-44 were enrolled into the baseline survey of a longitudinal study. Members of a health maintenance organisation were considered candidates for participation if they fulfilled membership, diagnostic, and treatment criteria based on automated review of electronic billing, claims, and pharmacy records. Diagnosis and treatment were confirmed by manual review of medical records. A telephone questionnaire was administered. A work related symptom score was assigned to each participant based on responses to questions about work related asthma symptoms, medication use, and symptom triggers. Blinded to participants' answers to these questions, two researchers independently reviewed the self-reported work histories and assigned exposure ratings. A final exposure score was then calculated. Participants with sufficient evidence for work related symptoms and exposure were classified as having WEA.
Of the 598 participants with complete data, 557 (93%) were working, and 136 (23%) fulfilled the criteria for WEA. Those with WEA were more likely to be male and to report that they had been bothered by asthma symptoms during the past seven days.
Workplace exacerbation of asthma was common in this study population, occurring in over a fifth of these adults with asthma. Physicians should consider that work can contribute to the exacerbation of symptoms when treating adults with asthma.
工作场所条件可能会促使哮喘病情恶化,但尚不清楚有多少成年哮喘患者经历过工作场所症状加重的情况。本调查的目的是确定哮喘工作场所加重(WEA)的患病率。
18 - 44岁的成年哮喘患者被纳入一项纵向研究的基线调查。如果健康维护组织的成员根据电子计费、理赔和药房记录的自动审查符合会员、诊断和治疗标准,则被视为参与候选人。通过人工审查病历确认诊断和治疗情况。进行电话问卷调查。根据对与工作相关的哮喘症状、药物使用和症状触发因素问题的回答,为每位参与者分配一个与工作相关的症状评分。在对这些问题的答案不知情的情况下,两名研究人员独立审查自我报告的工作经历并分配暴露等级。然后计算最终的暴露分数。有充分证据表明存在与工作相关症状和暴露的参与者被归类为患有WEA。
在598名有完整数据的参与者中,557人(93%)在工作,136人(23%)符合WEA标准。患有WEA的人更有可能是男性,并且报告在过去七天里受到哮喘症状的困扰。
在本研究人群中,哮喘工作场所加重情况很常见,在这些成年哮喘患者中超过五分之一的人出现这种情况。医生在治疗成年哮喘患者时应考虑到工作可能会导致症状加重。