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本文引用的文献

1
Workplace exacerbation of asthma symptoms: findings from a population-based study in Maine.工作场所哮喘症状加重:缅因州一项基于人群的研究结果
Arch Environ Health. 2003 Dec;58(12):781-8. doi: 10.1080/00039896.2003.10745072.
2
A descriptive study of work aggravated asthma.工作诱发哮喘的描述性研究。
Occup Environ Med. 2004 Jun;61(6):512-7. doi: 10.1136/oem.2003.008177.
3
A longitudinal study of adult-onset asthma incidence among HMO members.一项针对健康维护组织(HMO)成员中成人起病型哮喘发病率的纵向研究。
Environ Health. 2003 Aug 7;2(1):10. doi: 10.1186/1476-069X-2-10.
4
American Thoracic Society Statement: Occupational contribution to the burden of airway disease.美国胸科学会声明:职业因素对气道疾病负担的影响
Am J Respir Crit Care Med. 2003 Mar 1;167(5):787-97. doi: 10.1164/rccm.167.5.787.
5
Work-related exacerbation of asthma.
Int J Occup Environ Health. 2002 Oct-Dec;8(4):291-6. doi: 10.1179/107735202800338632.
6
Relation of occupational exposure to respiratory symptoms and asthma in a general population sample: self-reported versus interview-based exposure data.普通人群样本中职业暴露与呼吸道症状及哮喘的关系:自我报告与基于访谈的暴露数据
Am J Epidemiol. 2001 Sep 1;154(5):477-83. doi: 10.1093/aje/154.5.477.
7
The outcome of asthma related to workplace irritant exposures: a comparison of irritant-induced asthma and irritant aggravation of asthma.与工作场所刺激性物质暴露相关的哮喘结局:刺激性物质诱发的哮喘与哮喘加重的比较
Chest. 1999 Dec;116(6):1780-5. doi: 10.1378/chest.116.6.1780.
8
Surveillance of work-related asthma in selected U.S. states using surveillance guidelines for state health departments--California, Massachusetts, Michigan, and New Jersey, 1993-1995.1993 - 1995年,依据州卫生部门监测指南,对美国部分州(加利福尼亚州、马萨诸塞州、密歇根州和新泽西州)与工作相关的哮喘进行监测。
MMWR CDC Surveill Summ. 1999 Jun 25;48(3):1-20.
9
Long-term health and employment outcomes of occupational asthma and their determinants.职业性哮喘的长期健康和就业结局及其决定因素。
J Occup Environ Med. 1998 May;40(5):481-91. doi: 10.1097/00043764-199805000-00011.
10
A case series of 71 patients referred to a hospital-based occupational and environmental medicine clinic for occupational asthma.一组71例因职业性哮喘转诊至一家医院职业与环境医学门诊的病例。
West J Med. 1998 Feb;168(2):98-104.

患有哮喘的健康维护组织成员中工作场所病情加重的频率。

The frequency of workplace exacerbation among health maintenance organisation members with asthma.

作者信息

Henneberger P K, Derk S J, Sama S R, Boylstein R J, Hoffman C D, Preusse P A, Rosiello R A, Milton D K

机构信息

Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health/CDC, Morgantown, WV 26501, USA.

出版信息

Occup Environ Med. 2006 Aug;63(8):551-7. doi: 10.1136/oem.2005.024786. Epub 2006 Apr 6.

DOI:10.1136/oem.2005.024786
PMID:16601014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2078134/
Abstract

OBJECTIVES

Workplace conditions can potentially contribute to the worsening of asthma, yet it is unclear what percentage of adults with asthma experience workplace exacerbation of symptoms. The objective of this investigation was to determine the prevalence of workplace exacerbation of asthma (WEA).

METHODS

Adults with asthma aged 18-44 were enrolled into the baseline survey of a longitudinal study. Members of a health maintenance organisation were considered candidates for participation if they fulfilled membership, diagnostic, and treatment criteria based on automated review of electronic billing, claims, and pharmacy records. Diagnosis and treatment were confirmed by manual review of medical records. A telephone questionnaire was administered. A work related symptom score was assigned to each participant based on responses to questions about work related asthma symptoms, medication use, and symptom triggers. Blinded to participants' answers to these questions, two researchers independently reviewed the self-reported work histories and assigned exposure ratings. A final exposure score was then calculated. Participants with sufficient evidence for work related symptoms and exposure were classified as having WEA.

RESULTS

Of the 598 participants with complete data, 557 (93%) were working, and 136 (23%) fulfilled the criteria for WEA. Those with WEA were more likely to be male and to report that they had been bothered by asthma symptoms during the past seven days.

CONCLUSIONS

Workplace exacerbation of asthma was common in this study population, occurring in over a fifth of these adults with asthma. Physicians should consider that work can contribute to the exacerbation of symptoms when treating adults with asthma.

摘要

目的

工作场所条件可能会促使哮喘病情恶化,但尚不清楚有多少成年哮喘患者经历过工作场所症状加重的情况。本调查的目的是确定哮喘工作场所加重(WEA)的患病率。

方法

18 - 44岁的成年哮喘患者被纳入一项纵向研究的基线调查。如果健康维护组织的成员根据电子计费、理赔和药房记录的自动审查符合会员、诊断和治疗标准,则被视为参与候选人。通过人工审查病历确认诊断和治疗情况。进行电话问卷调查。根据对与工作相关的哮喘症状、药物使用和症状触发因素问题的回答,为每位参与者分配一个与工作相关的症状评分。在对这些问题的答案不知情的情况下,两名研究人员独立审查自我报告的工作经历并分配暴露等级。然后计算最终的暴露分数。有充分证据表明存在与工作相关症状和暴露的参与者被归类为患有WEA。

结果

在598名有完整数据的参与者中,557人(93%)在工作,136人(23%)符合WEA标准。患有WEA的人更有可能是男性,并且报告在过去七天里受到哮喘症状的困扰。

结论

在本研究人群中,哮喘工作场所加重情况很常见,在这些成年哮喘患者中超过五分之一的人出现这种情况。医生在治疗成年哮喘患者时应考虑到工作可能会导致症状加重。