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[脑积水治疗中的过度引流]

[Overdrainage in the treatment of hydrocephalus].

作者信息

Hirsch J F, Hoppe-Hirsch E, Sainte-Rose C

机构信息

Hôpital Necker-Enfants-Malades, service de neurochirurgie pédiatrique, Paris, France.

出版信息

Pediatrie. 1991;46(8-9):617-23.

PMID:1660122
Abstract

In infants or children, hydrocephalus is usually the consequence of an obstacle in the cerebro-spinal fluid (CSF) pathways and is most frequently treated by the insertion of a ventriculo-peritoneal shunt (rarely ventriculo-atrial). The CSF flow through such a shunt is equal to the ratio of the difference (DP) between the CSF input and output pressures over the valve resistance. When the child is in the upright position, a DP increase occurs due to the height of the hydrostatic column between the inlet and the shunt outlet. Thus if the shunt drains correctly in the prone position, it overdrains in the upright position. As the CSF flow through the shunt in standing patients is higher than the CSF secretion, the excess fluid will be taken out of the ventricles, resulting in pericerebral collections, slit ventricles or post-shunt craniostenoses. Many different techniques have been proposed to reduce overdrainage. The Orbis-Sigma shunt was designed in the "Service des Enfants-Malades" precisely for this purpose. In the upright position this shunt becomes a flow regulator and thus reduces overdrainage. Its use has decreased by 2-fold the number of mechanical complications related to overdrainage.

摘要

在婴儿或儿童中,脑积水通常是脑脊液(CSF)通路受阻的结果,最常见的治疗方法是插入脑室-腹腔分流管(很少使用脑室-心房分流管)。通过这种分流管的脑脊液流量等于脑脊液输入和输出压力之差(DP)与瓣膜阻力的比值。当儿童处于直立位时,由于入口和分流管出口之间静水压柱的高度,DP会增加。因此,如果分流管在俯卧位引流正常,那么在直立位时就会过度引流。由于站立患者通过分流管的脑脊液流量高于脑脊液分泌量,多余的液体将从脑室中排出,导致脑周积液、裂隙脑室或分流术后颅骨狭窄。已经提出了许多不同的技术来减少过度引流。奥比斯-西格玛分流管正是在“患病儿童服务部”为此目的而设计的。在直立位时,这种分流管成为流量调节器,从而减少过度引流。它的使用使与过度引流相关的机械并发症数量减少了两倍。

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