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接受放疗的癌症患者营养状况评估:一项前瞻性研究。

Evaluation of nutritional status in cancer patients receiving radiotherapy: a prospective study.

作者信息

Unsal Diclehan, Mentes Bulent, Akmansu Muge, Uner Aytug, Oguz Mehmet, Pak Yucel

机构信息

Gazi University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey.

出版信息

Am J Clin Oncol. 2006 Apr;29(2):183-8. doi: 10.1097/01.coc.0000198745.94757.ee.

Abstract

OBJECTIVES

The purpose of the present study was to evaluate the nutritional status of cancer patients receiving radiotherapy (RT) and to assess the possible contributions of nutritional support to patients with malnutrition.

METHODS

Prospectively, 207 patients referred to our outpatient radiotherapy department were included. The patients were classified according to tumor site (head/neck, breast, lung, stomach, or colorectal). Nutritional status at the onset, at the end of RT, and 3 and 6 months after irradiation was evaluated with the subjective global assessment (SGA). All of the patients were supported with additional portions of meal or standard enteral feeding formula during and after the irradiation period as long as they were in the moderately or severely malnourished groups, respectively.

RESULTS

At the onset, malnutrition was present in 31% of all patients, and it increased to 43% at the end of RT. This difference predominated in head/neck cancer patients. Malnutrition ratios in head/neck cancer patients at the onset and after RT were 24% and 88%, respectively. By a 6-month follow-up, the ratio of patients with malnutrition decreased to 8%. Nutritional status of all groups was found to improve during the 6-month follow-up period, except for the breast cancer group, which included no patients with severe malnutrition at any time.

CONCLUSION

The results of the present study may be helpful in planning an appropriate nutritional support for cancer patients undergoing radiotherapy according to the irradiation site.

摘要

目的

本研究旨在评估接受放疗(RT)的癌症患者的营养状况,并评估营养支持对营养不良患者的可能作用。

方法

前瞻性纳入207例转诊至我院门诊放疗科的患者。根据肿瘤部位(头颈部、乳腺、肺、胃或结直肠)对患者进行分类。采用主观全面评定法(SGA)评估放疗开始时、放疗结束时以及放疗后3个月和6个月时的营养状况。在放疗期间及放疗后,只要患者分别处于中度或重度营养不良组,均给予额外的膳食或标准肠内营养制剂。

结果

放疗开始时,31%的患者存在营养不良,放疗结束时这一比例增至43%。这种差异在头颈部癌症患者中最为明显。头颈部癌症患者放疗开始时和放疗后的营养不良比例分别为24%和88%。经过6个月的随访,营养不良患者的比例降至8%。除乳腺癌组在任何时候均无严重营养不良患者外,所有组的营养状况在6个月的随访期内均有所改善。

结论

本研究结果可能有助于根据放疗部位为接受放疗的癌症患者制定适当的营养支持方案。

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