Yang Xinyu, Guan Xin, Ding Yijing, Wang Jianglong, Li Xiaoyu
School of Nursing, Jilin University, Jilin Province, Changchun, 130000, China.
First Operating Room, The First Hospital of Jilin University, Changchun, China.
Support Care Cancer. 2025 May 29;33(6):512. doi: 10.1007/s00520-025-09546-y.
Postoperative malnutrition is very common in laryngeal cancer patients, which will lead to slower healing, lower quality of life, and increase patients' pain and medical cost. Enteral nutrition can better improve malnutrition in laryngeal cancer patients. The aim of this study was to provide an evidence-based basis for perioperative clinical practice in laryngeal cancer patients by systematically searching for interventions for perioperative enteral nutrition management.
According to the '6S' evidence resource model, evidence retrieval is searched from the top-down and collected relevant guidelines, clinical decision, system evaluation, and expert consensus. The retrieval time limit was from the database establishment to 1 April 2024. Two reviewers independently screened and evaluated the literature, and then extracted and summarised the evidence according to the JBI grading of evidence and recommendation system.
A total of 19 papers were ultimately included, including two clinical decisions, nine guidelines, one systematic evaluation, and seven expert consensus papers. By summarising and integrating the evidence, the final evidence was summarised in seven areas: nutritional risk screening and assessment, multidisciplinary team, preoperative nutritional support, postural management, postoperative nutritional support, discharge and follow-up, and health education, resulting in 29 best evidence.
This study summarises the best evidence on perioperative enteral nutrition for patients with laryngeal cancer in seven areas, and develops a programme of perioperative enteral nutrition interventions and practices for clinical staff or family caregivers to target patients with laryngeal cancer, and to improve clinical outcomes and quality of life for patients with laryngeal cancer.
术后营养不良在喉癌患者中非常常见，这会导致愈合缓慢、生活质量下降，并增加患者的痛苦和医疗费用。肠内营养能更好地改善喉癌患者的营养不良状况。本研究的目的是通过系统检索围手术期肠内营养管理的干预措施，为喉癌患者围手术期的临床实践提供循证依据。
根据“6S”证据资源模型，自上而下进行证据检索，收集相关指南、临床决策、系统评价和专家共识。检索时间范围为数据库建立至2024年4月1日。两名评审员独立筛选和评估文献，然后根据JBI证据分级和推荐系统提取并总结证据。
最终共纳入19篇文献，包括两项临床决策、九项指南、一项系统评价和七项专家共识文献。通过总结和整合证据，最终证据在营养风险筛查与评估、多学科团队、术前营养支持、体位管理、术后营养支持、出院与随访以及健康教育七个方面进行了总结，得出29条最佳证据。
本研究总结了喉癌患者围手术期肠内营养在七个方面的最佳证据，并为临床工作人员或家庭照顾者制定了针对喉癌患者的围手术期肠内营养干预方案和实践，以改善喉癌患者的临床结局和生活质量。
