Mogulkoc Nesrin, Kabasakal Yasemin, Ekren Pervin Korkmaz, Bishop Paul W
Department of Chest Medicine, Ege University Medical Faculty, Bornova, 35100 Izmir, Turkey.
J Clin Rheumatol. 2006 Apr;12(2):90-2. doi: 10.1097/01.rhu.0000209894.43413.67.
We report a case of anti-Jo-1 syndrome (a rare autoimmune condition that may manifest with various forms of interstitial lung disease), which in our case presented unusually with multiple pulmonary nodules, mimicking carcinoma. She subsequently developed pleural and pericardial effusions (which are rare in this syndrome), myopathy, and "mechanic's hand," with similar lesions on the feet. "Mechanic's foot" noted in this patient has not been previously described. She initially responded well to immunosuppression but has subsequently progressed to pulmonary fibrosis.
我们报告一例抗合成酶综合征（一种罕见的自身免疫性疾病，可能表现为各种形式的间质性肺疾病），在我们的病例中，其异常表现为多个肺结节，类似癌。随后她出现了胸腔和心包积液（在该综合征中较为罕见）、肌病以及“技工手”，足部也有类似病变。该患者出现的“技工足”此前未见报道。她最初对免疫抑制治疗反应良好，但随后进展为肺纤维化。
