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肉毒杆菌毒素注射可缓解孤立性高频下颌震颤。

Isolated high-frequency jaw tremor relieved by botulinum toxin injections.

作者信息

Gonzalez-Alegre Pedro, Kelkar Praful, Rodnitzky Robert L

机构信息

Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242-1101, USA.

出版信息

Mov Disord. 2006 Jul;21(7):1049-50. doi: 10.1002/mds.20878.

Abstract

Jaw tremor can be seen as a component of various neurological disorders such as essential tremor, Parkinson's disease, dystonia, branchial myoclonus, hereditary geniospasm, task-specific tremor, and Whipple's disease, as well as in normal situations such as shivering, and subclinical physiological jaw tremor. In most of these conditions, the jaw tremor is usually associated with tremor or other abnormal involuntary movements affecting additional body parts, and its frequency is lower than 12 Hz. Schrag and colleagues reported a patient with a high-frequency idiopathic jaw tremor, and they speculated it could be related to orthostatic tremor affecting the masseter muscles. We encountered a similar patient with intermittent rapid focal jaw tremor that was successfully treated with botulinum toxin injections to the masseters.

摘要

下颌震颤可作为多种神经系统疾病的一个组成部分,如特发性震颤、帕金森病、肌张力障碍、鳃肌阵挛、遗传性颏部痉挛、任务特异性震颤和惠普尔病,以及在诸如颤抖等正常情况下和亚临床生理性下颌震颤中出现。在这些情况中的大多数,下颌震颤通常与影响身体其他部位的震颤或其他异常不自主运动相关,且其频率低于12赫兹。施拉格及其同事报告了一名患有高频特发性下颌震颤的患者,他们推测这可能与影响咬肌的直立性震颤有关。我们遇到了一名类似的患者,其患有间歇性快速局灶性下颌震颤,通过向咬肌注射肉毒杆菌毒素成功治愈。

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