Moussa H M, Eckerman K F, Townsend L W
University of Tennessee, Department of Nuclear Engineering, Knoxville, TN 37996-2300, USA.
Radiat Prot Dosimetry. 2006;121(3):252-6. doi: 10.1093/rpd/ncl039. Epub 2006 Apr 7.
Estimates of the dose to the extrathoracic airway (nasal vestibule) from inhaled beta-emitting radionuclides, obtained using the respiratory tract model presented in Publication 66 of the International Commission on Radiological Protection, frequently predict that the basal cells in this region are the most highly irradiated tissues of the body. The dose to the basal cells is averaged over a layer of tissue 10 microm thick located at a depth of 40 microm into the airway assuming that charged particle equilibrium exists. Since the target (basal cell layer) is very small and thin (10 cm(2) area and 10 microm thickness), charged particle equilibrium does not exist. In this work the effect on the absorbed fraction of the lack of charged particle equilibrium is investigated.
使用国际放射防护委员会第66号出版物中提出的呼吸道模型,对吸入发射β射线的放射性核素时胸外气道(鼻前庭)所受剂量的估计,常常预测该区域的基底细胞是身体中受辐照程度最高的组织。假设存在带电粒子平衡,基底细胞所受剂量是在气道内40微米深度处10微米厚的一层组织上进行平均的。由于靶区(基底细胞层)非常小且薄(面积为10平方厘米,厚度为10微米),不存在带电粒子平衡。在这项工作中,研究了缺乏带电粒子平衡对吸收分数的影响。