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心肌梗死后β受体阻滞剂的应用:药理学原理与临床证据

Beta blockade in the post-myocardial infarction setting: pharmacologic rationale and clinical evidence.

作者信息

Williams Randall E

机构信息

Northwestern University School of Medicine, Evanston, IL, and Midwest Heart Specialists, Hoffman Estates, IL 60194, USA.

出版信息

Prev Cardiol. 2006 Spring;9(2):96-101. doi: 10.1111/j.1520-037x.2006.04690.x.

Abstract

The use of beta blockers reduces the risk of arrhythmias, reinfarction, and heart failure in both the immediate and long-term periods after a myocardial infarction. Every patient should be prescribed a beta blocker after a myocardial infarction unless there is a strong contraindication to therapy. Despite compelling evidence and recommendations, beta blockers remain an underutilized therapy in the post-myocardial infarction period. Evidence-based recommendations for the choice of agent and the practical implementation of beta blockers are reviewed.

摘要

在心肌梗死后的近期和长期,使用β受体阻滞剂可降低心律失常、再梗死和心力衰竭的风险。除非有强烈的治疗禁忌证,心肌梗死后的每位患者都应开具β受体阻滞剂。尽管有确凿的证据和建议,但在心肌梗死后阶段,β受体阻滞剂仍然是一种未得到充分利用的治疗方法。本文综述了关于β受体阻滞剂药物选择的循证推荐以及实际应用情况。

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