Yuan Xiaohui, Forman Barry Marc
Gene Regulation and Drug Discovery Department, The Beckman Research Institute at The City of Hope National Medical Center, Gonda Diabetes Research Center, Duarte, CA 91010, USA.
Nucl Recept Signal. 2005;3:e002. doi: 10.1621/nrs.03002. Epub 2005 Oct 21.
Illicit use of performance-enhancing steroids has proliferated among a wide range of professional and amateur athletes. This problem has attracted broad public attention and has led the United States Congress to draft legislation that proposes frequent testing of athletes. However, current testing protocols are inadequate as athletes can evade detection by using novel steroids that are unknown to authorities. We have developed a strategy that overcomes this limitation by virtue of its ability to detect "designer steroids" without prior knowledge of their existence.
非法使用增强性能的类固醇在众多职业和业余运动员中已泛滥成灾。这一问题已引起公众广泛关注，并促使美国国会起草立法，提议对运动员进行频繁检测。然而，目前的检测方案并不完善，因为运动员可以通过使用当局未知的新型类固醇来逃避检测。我们已经开发出一种策略，凭借其在事先不知道“设计类固醇”存在的情况下就能检测到它们的能力，克服了这一局限性。
