维甲酸相关孤儿受体α（ROR-α）在心血管内分泌学中的潜在作用。
Potential roles of ROR-alpha in cardiovascular endocrinology.
作者信息
Laitinen Saara, Staels Bart
机构信息
UR545 INSERM, Institut Pasteur de Lille, and Faculte de Pharmacie, Universite de Lille II, 1 rue du Pr Calmette 59019 Lille, France.
出版信息
Nucl Recept Signal. 2003;1:e011. doi: 10.1621/nrs.01011. Epub 2003 Oct 25.
Abstract
Atherosclerosis is a chronic disease of the arteries whose development involves a local inflammatory response characterized by the activation of different cells such as macrophages, T-lymphocytes, smooth muscle cells (SMCs) and endothelial cells (ECs). This review will summarize recent evidence for a modulatory role of the nuclear receptor ROR-alpha in cardiovascular disease.
摘要
动脉粥样硬化是一种动脉的慢性疾病，其发展涉及局部炎症反应，其特征是不同细胞（如巨噬细胞、T淋巴细胞、平滑肌细胞（SMC）和内皮细胞（EC））的激活。本综述将总结核受体ROR-α在心血管疾病中调节作用的最新证据。
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