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Treatment of experimental status epilepticus in immature rats: dissociation between anticonvulsant and antiepileptogenic effects.幼鼠实验性癫痫持续状态的治疗：抗惊厥作用与抗癫痫发生作用的分离
Pediatr Res. 2006 Feb;59(2):237-43. doi: 10.1203/01.pdr.0000196333.16608.30.
2
Spatial learning deficits and emotional impairments in pentylenetetrazole-kindled rats.戊四氮点燃大鼠的空间学习缺陷与情绪障碍
Epilepsy Behav. 2005 Dec;7(4):629-38. doi: 10.1016/j.yebeh.2005.08.019. Epub 2005 Oct 24.
3
Effects of pentylenetetrazole-induced status epilepticus on behavior, emotional memory and learning in immature rats.戊四氮诱导的癫痫持续状态对幼鼠行为、情绪记忆和学习的影响。
Epilepsy Behav. 2005 Jun;6(4):537-42. doi: 10.1016/j.yebeh.2005.03.002. Epub 2005 Apr 26.
4
A pentylenetetrazole-induced generalized seizure in early life enhances the efficacy of muscarinic receptor coupling to G-protein in hippocampus and neocortex of adult rat.早年戊四氮诱发的全身性癫痫发作可增强成年大鼠海马和新皮质中毒蕈碱受体与G蛋白偶联的效能。
Eur J Neurosci. 2005 Apr;21(7):1828-36. doi: 10.1111/j.1460-9568.2005.04026.x.
5
Susceptibility of immature and adult brains to seizure effects.未成熟脑和成年脑对癫痫发作影响的易感性。
Lancet Neurol. 2004 Oct;3(10):608-17. doi: 10.1016/S1474-4422(04)00881-6.
6
Status epilepticus in immature rats leads to behavioural and cognitive impairment and epileptogenesis.幼鼠癫痫持续状态会导致行为和认知障碍以及癫痫发生。
Eur J Neurosci. 2004 Jun;19(12):3255-65. doi: 10.1111/j.0953-816X.2004.03410.x.
7
Seizure-induced changes in place cell physiology: relationship to spatial memory.癫痫发作引起的位置细胞生理学变化：与空间记忆的关系。
J Neurosci. 2003 Dec 17;23(37):11505-15. doi: 10.1523/JNEUROSCI.23-37-11505.2003.
8
Long-term effects of status epilepticus in the immature brain are specific for age and model.癫痫持续状态对未成熟大脑的长期影响因年龄和模型而异。
Epilepsia. 2003 Apr;44(4):518-28. doi: 10.1046/j.1528-1157.2003.48802.x.
9
Pentylenetetrazol-induced recurrent seizures in rat pups: time course on spatial learning and long-term effects.戊四氮诱导的幼鼠反复癫痫发作：对空间学习的时间进程及长期影响
Epilepsia. 2002 Jun;43(6):567-73. doi: 10.1046/j.1528-1157.2002.29101.x.
10
Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats.癫痫持续状态会导致未成熟大鼠丘脑背内侧核的坏死性损伤。
J Neurosci. 2001 May 15;21(10):3593-9. doi: 10.1523/JNEUROSCI.21-10-03593.2001.

Invulnerability of the immature brain to seizures: do dogmas have nine lives?

作者信息

Wasterlain Claude G

出版信息

Epilepsy Curr. 2006 Mar-Apr;6(2):59-61. doi: 10.1111/j.1535-7511.2006.00099.x.

DOI:10.1111/j.1535-7511.2006.00099.x
PMID:16604205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1408286/
Abstract
摘要