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两种经皮胆红素测定仪——美能达无创黄疸仪JM103和光谱x线黄疸仪——在泰国新生儿中的比较。

Comparison of two transcutaneous bilirubinometers--Minolta AirShields Jaundice Meter JM103 and Spectrx Bilicheck--in Thai neonates.

作者信息

Sanpavat Suwimol, Nuchprayoon Issarang

机构信息

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 2005 Nov;36(6):1533-7.

Abstract

Transcutaneous bilirubin (TcB) has been reported to have a high correlation with serum bilirubin. The objectives of this study were: (1) to compare the accuracy of two transcutaneous bilirubinometer (Minolto AirShields Jaundice Meter, JM103 (JM) and SpectRx, Bilicheck (BC) in estimating total serum bilirubin (TSB) levels; and (2) to assess the predictive ability of transcutaneous bilirubin in relation to specific selected TSB levels. A total of 154 measurements of TcB, using JM and BC, and TSB were recruited from 134 term and near-term infants. Postnatal ages ranged from 19 to 160 hours (x = 64.7, SD = 25.6). TSB levels ranged from 4.5 to 17.5 mg/dl (x = 10.4, SD = 2.5). The correlation coefficients between TcB (JM and BC) and TSB measurements were significant and similar (r 0.80 and 0.82, respectively). The errors of distribution were, for TSB and TcB-JM, the mean difference of 0.7 mg/dl (SD 1.6 mg/dl and 95% confidence interval of the mean (CI) 0.4 and 1.0]; and, for TSB and TcB-BC, the mean difference of -0.6 mg/dl (SD 1.5 mg/dl and 95% CI -0.4 and -0.8). TcB-JM had a tendency to underestimate TSB levels, and TcB-BC had a tendency to overestimate TSB levels. The sensitivity of BC was higher, but specificity was lower, than JM in corresponding to different TSB levels, except at a TSB level of 15 mg/dl when both instruments yielded 100% sensitivity. The accuracy of JM in predicting TSB was higher than BC at all TSB levels. Operating the JM was simple and uncomplicated. It would be suitable for clinical use when a number of personnel perform the measurement.

摘要

据报道,经皮胆红素(TcB)与血清胆红素高度相关。本研究的目的是:(1)比较两种经皮胆红素仪(美能达AirShields黄疸仪,JM103(JM)和SpectRx Bilicheck(BC))在估计总血清胆红素(TSB)水平方面的准确性;(2)评估经皮胆红素相对于特定选定TSB水平的预测能力。从134名足月儿和近足月儿中收集了总共154次使用JM和BC测量的TcB以及TSB数据。出生后年龄范围为19至160小时(x = 64.7,标准差 = 25.6)。TSB水平范围为4.5至17.5mg/dl(x = 10.4,标准差 = 2.5)。TcB(JM和BC)与TSB测量之间的相关系数显著且相似(分别为r = 0.80和0.82)。对于TSB和TcB-JM,分布误差为平均差异0.7mg/dl(标准差1.6mg/dl,平均95%置信区间(CI)为0.4至1.0);对于TSB和TcB-BC,平均差异为 -0.6mg/dl(标准差1.5mg/dl,95%CI为 -0.4至 -0.8)。TcB-JM有低估TSB水平的趋势,而TcB-BC有高估TSB水平的趋势。除了在TSB水平为15mg/dl时两种仪器的灵敏度均为100%外,在对应不同TSB水平时,BC的灵敏度高于JM,但特异性低于JM。在所有TSB水平上,JM预测TSB的准确性均高于BC。操作JM简单易行。当有多名人员进行测量时,它适合临床使用。

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