Ghosh P K, Murthy R S R
Drug Delivery Research Laboratory, Pharmacy Department, The M.S. University of Baroda, Vadodara, India.
Curr Drug Deliv. 2006 Apr;3(2):167-80. doi: 10.2174/156720106776359168.
Microemulsions are clear, transparent, thermodynamically stable dispersions of oil and water, stabilised by an interfacial film of surfactant frequently in combination with a co-surfactant. Recently, there has been a considerable interest for the microemulsion formulation, for the delivery of hydrophilic as well as lipophilic drug as drug carriers because of its improved drug solubilisation capacity, long shelf life, easy of preparation and improvement of bioavailability. In this present review, we discuss about the various advantages of microemulsion in pharmaceuticals, along with its composition variables, physicochemical characterisation etc. The potential use of microemulsion for therapeutic application is also discussed.
微乳剂是由油和水形成的澄清、透明、热力学稳定的分散体系，通常由表面活性剂与助表面活性剂形成的界面膜来稳定。近年来，微乳剂作为药物载体用于亲水性和亲脂性药物的递送备受关注，因为它具有提高药物溶解能力、保质期长、易于制备和提高生物利用度等优点。在本综述中，我们讨论了微乳剂在制药领域的各种优势，以及其组成变量、物理化学特性等。还讨论了微乳剂在治疗应用中的潜在用途。
