Choi Y J, Yang K H, Gang S J, Kim B K, Kim S M
Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.
J Korean Med Sci. 1991 Jun;6(2):157-63. doi: 10.3346/jkms.1991.6.2.157.
An extremely rare case of malignant glomus tumor originating in the superior mediastinum was evaluated immunohistochemically and ultrastructurally. A 78-year-old woman who had been suffering from dysphagia and dyspnea had poorly-defined soft tissue mass, 4.5 x 2.5cm, in the superior mediastinum with direct invasion into the esophagus, trachea, and bilateral thyroid glands. This case is believed to be unique in several respects. There were neither recognizable findings of benign glomus tumor nor sarcomatous areas, in contrast to the previously reported cases. A definite direct invasion into the surrounding organs was identified. We therefore interpreted this case as primary malignant glomus tumor, not as glomangiosarcoma arising in a benign glomus tumor.
对一例极其罕见的起源于上纵隔的恶性血管球瘤进行了免疫组织化学和超微结构评估。一名78岁女性，因吞咽困难和呼吸困难就诊，上纵隔有一个边界不清的软组织肿块，大小为4.5×2.5cm，直接侵犯食管、气管和双侧甲状腺。该病例在几个方面被认为是独特的。与先前报道的病例相比，既没有良性血管球瘤的典型表现，也没有肉瘤区域。发现有明确的向周围器官的直接侵犯。因此，我们将该病例解释为原发性恶性血管球瘤，而非起源于良性血管球瘤的血管肉瘤。
