Böör A, Jurkovic I, Janík M, Vajó J, Kocan P, Ponist J, Dudriková K, Krajcár R, Stubna J
Department of Pathology, Medical Faculty, P. J. Safárik University and Louis Pasteur Faculty Hospital, Kosice, Slovak Republic.
Cesk Patol. 2000 Oct;36(4):156-9.
An unusual location of a benign glomus tumour, outside of the constantly located regions, e.g. in the subungual location or deeply sited in extremities, was diagnosed in a 56-year-old white female in her posterior upper mediastinum. The single similar case report was published before the era of electron microscopy and immunohistochemistry and single cases of atypical and malignant forms in this unusual location were published only recently. The tumour measuring 5 x 4 x 2 centimeters has caused cough and was associated with occasional righ-sided chest pain. Its rich vascular supply has caused intensive intraoperative bleeding. The postoperative course was uneventful and the patient is free of neoplastic disease or symptoms six years after surgery. Numerous mast cells present within the tumour's interstices must be considered in relation to the possible pathogenesis of the up to now unexplained pain in glomus tumours.
一名56岁白人女性的后上纵隔被诊断出患有良性血管球瘤,其位置不寻常,不在常见部位,如甲下或四肢深部。唯一一份类似病例报告发表于电子显微镜和免疫组织化学时代之前,而近期才发表了该不寻常部位非典型和恶性形式的单例报告。肿瘤大小为5×4×2厘米,引发咳嗽,并伴有偶尔的右侧胸痛。其丰富的血供导致术中出血严重。术后恢复顺利,患者术后六年无肿瘤疾病或症状。肿瘤间隙中存在大量肥大细胞,这一点必须与血管球瘤目前无法解释的疼痛的可能发病机制联系起来考虑。