Liu Je-Ruei, Wang Sheng-Yao, Chen Ming-Ju, Chen Hsiao-Ling, Yueh Pei-Ying, Lin Chin-Wen
Department of Biotechnology, National Formosa University, Taiwan.
Br J Nutr. 2006 May;95(5):939-46. doi: 10.1079/bjn20061752.
This study aimed to evaluate the hypocholesterolaemic property of milk-kefir and soyamilk-kefir. Male hamsters were fed on a cholesterol-free or cholesterol-enriched diet containing 10 % skimmed milk, milk-kefir, soyamilk or soyamilk-kefir for a period of 8 weeks. The soyamilk, milk-kefir and soyamilk-kefir diets all tended towards a lowering of serum triacylglycerol and total cholesterol concentrations, and a reduction of cholesterol accumulation in the liver, the decrease in serum cholesterol concentration being mainly in the non-HDL fraction. The soyamilk-kefir diet led to a significant increase in the faecal excretion of neutral sterols and bile acids compared with the other two diets. The soyamilk-kefir diet also elicited a significant decrease in the serum ratio of non-HDL-cholesterol to HDL-cholesterol, compared with the control, than was the case for the other diets. These findings demonstrate that soyamilk-kefir may be considered to be among the more promising food components in terms of preventing CVD through its hypocholesterolaemic action.
本研究旨在评估开菲尔牛奶和豆奶开菲尔的降胆固醇特性。雄性仓鼠被喂食不含胆固醇或富含胆固醇的饮食，其中含有10%的脱脂牛奶、开菲尔牛奶、豆奶或豆奶开菲尔，为期8周。豆奶、开菲尔牛奶和豆奶开菲尔饮食均倾向于降低血清三酰甘油和总胆固醇浓度，并减少肝脏中的胆固醇积累，血清胆固醇浓度的降低主要发生在非高密度脂蛋白部分。与其他两种饮食相比，豆奶开菲尔饮食导致中性固醇和胆汁酸的粪便排泄显著增加。与对照组相比，豆奶开菲尔饮食还引起血清非高密度脂蛋白胆固醇与高密度脂蛋白胆固醇的比率显著降低，这一情况比其他饮食更为明显。这些发现表明，豆奶开菲尔因其降胆固醇作用，在预防心血管疾病方面可能被认为是较有前景的食物成分之一。
