Liebler-Tenorio Elisabeth M, Pabst Reinhard
Friedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Naumburger Str. 96 a, 07743 Jena, Germany.
Vet Res. 2006 May-Jun;37(3):257-80. doi: 10.1051/vetres:2006001. Epub 2006 Feb 23.
Mucosa-associated lymphoid tissue (MALT) is defined as an organized lymphoid tissue in the mucosa that samples antigens. The morphological characteristics that distinguish MALT from lymphoid infiltrates are discussed. MALT has been extensively investigated in laboratory animals, while knowledge in cattle, sheep, goats, pigs and horses that are summarized under the term farm animals in this review is fragmentary. Literature data about the distribution, morphology, function and involvement in infectious diseases of MALT in farm animals are described. The understanding of specific features of MALT in other species than laboratory animals is important for comparative research, in order to understand pathological and immunological processes in the respective species and as a potential route of vaccination of mucosal surfaces.
黏膜相关淋巴组织（MALT）被定义为黏膜中对抗原进行采样的有组织的淋巴组织。文中讨论了将MALT与淋巴浸润区分开来的形态学特征。MALT已在实验动物中得到广泛研究，而在本综述中统称为农场动物的牛、羊、山羊、猪和马方面的知识则较为零散。本文描述了有关农场动物MALT的分布、形态、功能以及在传染病中的作用的文献数据。了解实验动物以外其他物种MALT的特定特征对于比较研究很重要，有助于理解各物种的病理和免疫过程，并作为黏膜表面疫苗接种的潜在途径。
