• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Is kinetoplastid pan-editing the result of an evolutionary balancing act?

作者信息

Speijer Dave

机构信息

Department of Medical Biochemistry, AMC, Amsterdam, The Netherlands.

出版信息

IUBMB Life. 2006 Feb;58(2):91-6. doi: 10.1080/15216540600551355.

DOI:10.1080/15216540600551355
PMID:16611574
Abstract

Kinetoplastid U-insertion/deletion type editing is a highly elaborate process to generate translationally competent mitochondrial mRNAs. All evolutionary models to explain its origin and extent in present day organisms lack a convincing description of the advantage(s) responsible for an active increase of the editing potential. This advantage can be found in the gene fragmentation that is inherent in pan-editing which gives protection against loss of temporarily non expressed mitochondrial genes during periods of intense intraspecies competition.

摘要

相似文献

1
Is kinetoplastid pan-editing the result of an evolutionary balancing act?
IUBMB Life. 2006 Feb;58(2):91-6. doi: 10.1080/15216540600551355.
2
In vitro assays for kinetoplastid U insertion-deletion editing and associated activities.动质体U插入缺失编辑及相关活性的体外测定。
Methods Mol Biol. 2004;265:251-72. doi: 10.1385/1-59259-775-0:251.
3
Strategies of kinetoplastid cryptogene discovery and analysis.动质体隐蔽基因的发现与分析策略。
Methods Enzymol. 2007;424:127-39. doi: 10.1016/S0076-6879(07)24006-6.
4
Gene Loss and Error-Prone RNA Editing in the Mitochondrion of Perkinsela, an Endosymbiotic Kinetoplastid.内共生动质体 Perkinsela 线粒体中的基因丢失和易出错的 RNA 编辑
mBio. 2015 Dec 1;6(6):e01498-15. doi: 10.1128/mBio.01498-15.
5
Diversity and evolution of mitochondrial RNA editing systems.线粒体RNA编辑系统的多样性与进化
IUBMB Life. 2003 Apr-May;55(4-5):227-33. doi: 10.1080/1521654031000119425.
6
Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates.动质体鞭毛虫线粒体基因组和转录组的不明复杂性
Curr Genet. 2005 Nov;48(5):277-99. doi: 10.1007/s00294-005-0027-0. Epub 2005 Nov 4.
7
The evolution of RNA editing in kinetoplastid protozoa.动质体原生动物中RNA编辑的进化
Biosystems. 1992;28(1-3):41-5. doi: 10.1016/0303-2647(92)90006-k.
8
Evolutionary conservation of RNA editing in the genus Leishmania.利什曼原虫属中RNA编辑的进化保守性。
Infect Genet Evol. 2008 May;8(3):378-80. doi: 10.1016/j.meegid.2007.12.009. Epub 2008 Jan 5.
9
Making sense of scrambled genomes.
Science. 2008 Feb 15;319(5865):901-2; author reply 901-2. doi: 10.1126/science.319.5865.901a.
10
Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the Myxomycota.黏菌线粒体小亚基rRNA中RNA编辑位点的进化
Methods Enzymol. 2007;424:197-220. doi: 10.1016/S0076-6879(07)24009-1.

引用本文的文献

1
Hydrophobicity-Driven Increases in Editing in Mitochondrial mRNAs during the Evolution of Kinetoplastids.疏水性驱动的顶复门生物中线粒体 mRNA 编辑的进化增加。
Mol Biol Evol. 2023 Apr 4;40(4). doi: 10.1093/molbev/msad081.
2
Constructive Neutral Evolution 20 Years Later.建设性中性进化 20 年后
J Mol Evol. 2021 Apr;89(3):172-182. doi: 10.1007/s00239-021-09996-y. Epub 2021 Feb 19.
3
Cell-line specific RNA editing patterns in Trypanosoma brucei suggest a unique mechanism to generate protein variation in a system intolerant to genetic mutations.
在布鲁氏锥虫中,细胞系特异性 RNA 编辑模式表明了一种在遗传突变不耐受的系统中产生蛋白质变异的独特机制。
Nucleic Acids Res. 2020 Feb 20;48(3):1479-1493. doi: 10.1093/nar/gkz1131.
4
Massive mitochondrial DNA content in diplonemid and kinetoplastid protists.原生动物双滴虫目和动基体目生物中存在大量的线粒体 DNA 含量。
IUBMB Life. 2018 Dec;70(12):1267-1274. doi: 10.1002/iub.1894. Epub 2018 Oct 6.
5
Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool.锥虫线粒体 RNA 编辑:专用图谱工具揭示出的极其复杂的转录组。
Nucleic Acids Res. 2018 Jan 25;46(2):765-781. doi: 10.1093/nar/gkx1202.
6
Mitochondrial dual-coding genes in Trypanosoma brucei.布氏锥虫中的线粒体双编码基因。
PLoS Negl Trop Dis. 2017 Oct 9;11(10):e0005989. doi: 10.1371/journal.pntd.0005989. eCollection 2017 Oct.
7
Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes.多个预编辑的 mRNA 中的 G-四链体结构表明 RNA 编辑在原生动物中的进化驱动力。
Sci Rep. 2016 Jul 20;6:29810. doi: 10.1038/srep29810.
8
Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex.双核处理:MRB1 是一种新兴的动质体 RNA 编辑复合物。
Trends Parasitol. 2013 Feb;29(2):91-9. doi: 10.1016/j.pt.2012.11.005. Epub 2013 Jan 8.
9
Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei.鉴定两个新的 RNA 结合蛋白基因的功能,它们影响布氏锥虫的线粒体转录本。
RNA. 2012 Oct;18(10):1846-61. doi: 10.1261/rna.033852.112. Epub 2012 Aug 16.
10
Gene fragmentation: a key to mitochondrial genome evolution in Euglenozoa?基因片段化:眼虫动物线粒体基因组进化的关键?
Curr Genet. 2011 Aug;57(4):225-32. doi: 10.1007/s00294-011-0340-8. Epub 2011 May 5.